Literature DB >> 3120399

Immunohistochemical distribution of vitamin B12 R-binder in renal cell carcinoma.

K Ogawa1, H Kudo, Y C Kim, Y Nakashima, G Ohshio, H Yamabe, M Inada, Y Hamashima.   

Abstract

Renal cell carcinomas and normal kidney tissues were examined for the expression of vitamin B12 R-binder by the indirect immunoperoxidase method. In normal kidney tissue, the presence of the vitamin B12 R-binder was shown to be confined to the straight portion (pars recta) of proximal tubules. Seven of the 38 cases of renal cell carcinoma (18%) expressed the vitamin B12 R-binder antigen. This provides a further evidence of the proximal tubular nature of renal cell carcinoma, and suggests that a small proportion of renal cell carcinomas originate from the straight portion of the renal proximal tubules.

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Year:  1987        PMID: 3120399     DOI: 10.1007/bf00750726

Source DB:  PubMed          Journal:  Virchows Arch A Pathol Anat Histopathol        ISSN: 0174-7398


  21 in total

1.  Ultrastructure of the clear cells in renal carcinomas and its importance for the demonstration of their renal origin.

Authors:  C OBERLING; M RIVIERE; F HAGUENAU
Journal:  Nature       Date:  1960-04-30       Impact factor: 49.962

2.  Ultrastructural pathology of human renal cell tumors.

Authors:  M Tannenbaum
Journal:  Pathol Annu       Date:  1971

3.  Granulocyte colony stimulating activity and vitamin B12 binding proteins in human urine.

Authors:  E L Gibson; V Herbert; W A Robinson
Journal:  Br J Haematol       Date:  1974-10       Impact factor: 6.998

4.  Characterization and isolation of specific renal tubular epithelial antigens.

Authors:  T S Edgington; R J Glassock; J I Watson; F J Dixon
Journal:  J Immunol       Date:  1967-12       Impact factor: 5.422

5.  Prognosis in renal carcinoma.

Authors:  L E Böttiger
Journal:  Cancer       Date:  1970-10       Impact factor: 6.860

Review 6.  Human vitamin B12 transport proteins.

Authors:  R H Allen
Journal:  Prog Hematol       Date:  1975

7.  Cobalamin-binding proteins in human urine: identification and quantitation.

Authors:  V Wahlstedt; R Gräsbeck
Journal:  J Lab Clin Med       Date:  1985-10

8.  Immunohistochemical localisation of vitamin B12 R-binder in the human digestive tract.

Authors:  H Kudo; M Inada; G Ohshio; Y Wakatsuki; K Ogawa; Y Hamashima; T Miyake
Journal:  Gut       Date:  1987-03       Impact factor: 23.059

9.  Specificity analysis of mouse monoclonal antibodies defining cell surface antigens of human renal cancer.

Authors:  C L Finstad; C Cordon-Cardo; N H Bander; W F Whitmore; M R Melamed; L J Old
Journal:  Proc Natl Acad Sci U S A       Date:  1985-05       Impact factor: 11.205

10.  Cellular origin and differentiation of renal carcinomas. A fluorescence microscopic study with kidney-specific antibodies, antiintermediate filament antibodies, and lectins.

Authors:  H Holthöfer; A Miettinen; R Paasivuo; V P Lehto; E Linder; O Alfthan; I Virtanen
Journal:  Lab Invest       Date:  1983-09       Impact factor: 5.662

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  1 in total

1.  Overexpression of Transcobalamin 1 is an Independent Negative Prognosticator in Rectal Cancers Receiving Concurrent Chemoradiotherapy.

Authors:  Yi-Ying Lee; Yu-Ching Wei; Yu-Feng Tian; Ding-Ping Sun; Ming-Jen Sheu; Ching-Chieh Yang; Li-Ching Lin; Chen-Yi Lin; Chung-Hsi Hsing; Wan-Shan Li; Chien-Feng Li; Pei-Ling Hsieh; Ching-Yih Lin
Journal:  J Cancer       Date:  2017-05-12       Impact factor: 4.207

  1 in total

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