Literature DB >> 31195792

Impact of mast cells in systemic lupus erythematosus: can inflammation be inhibited?

Al Caraffa1, C E Gallenga2, S K Kritas3, G Ronconi4, P Conti5.   

Abstract

Systemic lupus erythematosus (SLE), is a complex chronic inflammatory autoimmune disease, with rheumatological manifestations, which afflicts mainly women. SLE presents various heterogeneous clinical aspects and different pathogeneses and involves the production of anti- DNA autoantibodies which are deposited as immune complexes in various organs and tissues, provoking inflammation. These diseases cause multiple tissue and organ damage in arthritis, skin lesions, hematologic changes, renal and neurologic disorders, and others (Table I). In SLE, serum contains anti-nucleus antibodies and anti-DNA antibodies that can be important biomarkers for patients suffering from this disease. Copyright 2019 Biolife Sas www.biolifesas.org.

Entities:  

Keywords:  cytokines; inflammation; IL-37; mast cell; systemic lupus erythematosus

Mesh：

Substances：

Year:  2019        PMID： 31195792

Source DB:  PubMed          Journal:  J Biol Regul Homeost Agents        ISSN： 0393-974X            Impact factor:   1.711


  6 in total

Review 1.  Advances in Mast Cell Activation by IL-1 and IL-33 in Sjögren's Syndrome: Promising Inhibitory Effect of IL-37.

Authors:  Pio Conti; Luisa Stellin; Alesssandro Caraffa; Carla E Gallenga; Rhiannon Ross; Spyros K Kritas; Ilias Frydas; Ali Younes; Paolo Di Emidio; Gianpaolo Ronconi
Journal:  Int J Mol Sci       Date:  2020-06-16       Impact factor: 5.923

2.  Anti-inflammatory cytokines IL-35 and IL-10 block atherogenic lysophosphatidylcholine-induced, mitochondrial ROS-mediated innate immune activation, but spare innate immune memory signature in endothelial cells.

Authors:  Xinyuan Li; Pu Fang; Yu Sun; Ying Shao; William Y Yang; Xiaohua Jiang; Hong Wang; Xiaofeng Yang
Journal:  Redox Biol       Date:  2019-11-06       Impact factor: 11.799

3.  Expression and existence forms of mast cell activating molecules and their antibodies in systemic lupus erythematosus.

Authors:  Yuping Wang; Tengkai Wang; Meijuan Cai; Shuzhen Zhu; Lijun Song; Qian Wang
Journal:  Immun Inflamm Dis       Date:  2021-11-16

Review 4.  The Role and Impact of Extracellular Vesicles in the Modulation and Delivery of Cytokines during Autoimmunity.

Authors:  Mohammed Tayab Hussain; Asif Jilani Iqbal; Lucy Victoria Norling
Journal:  Int J Mol Sci       Date:  2020-09-26       Impact factor: 5.923

5.  Co-Stimulation of Purinergic P2X4 and Prostanoid EP3 Receptors Triggers Synergistic Degranulation in Murine Mast Cells.

Authors:  Kazuki Yoshida; Makoto Tajima; Tomoki Nagano; Kosuke Obayashi; Masaaki Ito; Kimiko Yamamoto; Isao Matsuoka
Journal:  Int J Mol Sci       Date:  2019-10-17       Impact factor: 5.923

6.  The Absence of Tryptase Mcpt6 Causes Elevated Cellular Stress in Response to Modulation of the Histone Acetylation Status in Mast Cells.

Authors:  Sebastin Santosh Martin; Fabio Rabelo Melo; Gunnar Pejler
Journal:  Cells       Date:  2019-10-02       Impact factor: 6.600
  6 in total

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