Literature DB >> 31191126

Vasectomy reversal utilizing fibrin glue.

G Luke Machen1, Ali M Mahmoud2, Colin E Kleinguetl1, Wencong Chen3, Stephanie E Harris1, Erin T Bird1.   

Abstract

Over 500,000 men in America have a vasectomy annually; 2% to 6% of these individuals later elect to have a vasectomy reversal. Vasovasostomies are typically performed using a single- or double-layer closure, with no demonstrated difference between the two in terms of success rates. In 2005, Ho et al described a microscopic technique in which three full-thickness sutures are used and the anastomosis is reinforced with fibrin glue. At our institution, a similar technique has been used for >10 years. To describe our experience, a retrospective chart review was undertaken. Patient demographic information and operative characteristics were analyzed. In each case, fibrin glue was circumferentially applied to reinforce the anastomosis. The overall patency rate was 88.4%, and rates comparing individuals who had their vasectomy reversal within 10 years of vasectomy reached statistical significance with an odds ratio of 2.91 (P = 0.048). Median operative time was 94 minutes. Other demographic variables analyzed did not have a correlation with patency. In conclusion, our technique provides acceptable patency rates, especially with obstructive intervals of 10 years or less, while likely resulting in cost savings given the decreased operating room time and suture used.

Entities:  

Keywords:  Fibrin glue; male infertility; vasectomy reversal

Year:  2019        PMID: 31191126      PMCID: PMC6541075          DOI: 10.1080/08998280.2018.1548839

Source DB:  PubMed          Journal:  Proc (Bayl Univ Med Cent)        ISSN: 0899-8280


  14 in total

1.  Fibrin glue vasal anastomosis compared to conventional sutured vasovasostomy in the rat.

Authors:  J I Silverstein; B C Mellinger
Journal:  J Urol       Date:  1991-06       Impact factor: 7.450

2.  Vasectomy and vasectomy reversal: important issues. Preface.

Authors:  Jay I Sandlow; Harris M Nagler
Journal:  Urol Clin North Am       Date:  2009-08       Impact factor: 2.241

Review 3.  Demographics of vasectomy--USA and international.

Authors:  John M Pile; Mark A Barone
Journal:  Urol Clin North Am       Date:  2009-08       Impact factor: 2.241

Review 4.  Outcomes of microsurgical vasovasostomy for vasectomy reversal: a meta-analysis and systematic review.

Authors:  Lindsey A Herrel; Michael Goodman; Marc Goldstein; Wayland Hsiao
Journal:  Urology       Date:  2015-04       Impact factor: 2.649

5.  Fibrin glue assisted 3-suture vasovasostomy.

Authors:  Khai-Linh V Ho; Matthew N Witte; Erin T Bird; Samuel Hakim
Journal:  J Urol       Date:  2005-10       Impact factor: 7.450

6.  Comparative Cost-Effectiveness Analysis of Modified 1-Layer versus Formal 2-Layer Vasovasostomy Technique.

Authors:  Yaw A Nyame; Paurush Babbar; Nima Almassi; Alan S Polackwich; Edmund Sabanegh
Journal:  J Urol       Date:  2015-09-24       Impact factor: 7.450

7.  One-layer vasovasostomy: microsurgical versus loupe-assisted.

Authors:  Sang Hyun Jee; Young Kwon Hong
Journal:  Fertil Steril       Date:  2010-01-13       Impact factor: 7.329

Review 8.  Current status of vasectomy reversal.

Authors:  J Ullrich Schwarzer; Heiko Steinfatt
Journal:  Nat Rev Urol       Date:  2013-02-12       Impact factor: 14.432

9.  Results of 1,469 microsurgical vasectomy reversals by the Vasovasostomy Study Group.

Authors:  A M Belker; A J Thomas; E F Fuchs; J W Konnak; I D Sharlip
Journal:  J Urol       Date:  1991-03       Impact factor: 7.450

Review 10.  Vasectomy reversal: a clinical update.

Authors:  Abhishek P Patel; Ryan P Smith
Journal:  Asian J Androl       Date:  2016 May-Jun       Impact factor: 3.285

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