Literature DB >> 31191123

Impact of frailty and anticoagulation status on readmission and mortality rates following falls in patients over 80.

Chad Hall1, Shannon Essler2, Jad Dandashi3, Matthew Corrigan3, Yolanda Muñoz-Maldonado4, Andrew Juergens2, Scott Wieters2, Dorian Drigalla2, Justin L Regner1.   

Abstract

Falls are the leading cause of trauma-related mortality in geriatric patients. We hypothesized that frailty and anticoagulation status are risk factors for readmission and mortality following falls in patients >80 years. A retrospective review was performed on patients over 80 years old who presented to our level 1 trauma center for a fall and underwent a computed tomography of the head between January 2014 and January 2016. Frailty was assessed via the Rockwood Frailty Score. Clinical outcomes were death, readmission, recurrent falls, and delayed intracranial hemorrhage. Of 803 fall-related encounters, 173 patients over 80 years old were identified for inclusion. The 30-day readmission rate was 17.5% and was associated with an increased 6-month mortality (P = 0.01). One-year and 2-year mortality rates were 28% and 47%, respectively. Frailty was the strongest predictor of 6-month and overall mortality (P < 0.01). Anticoagulation status did not significantly influence these outcomes. The recurrent fall rate was 21%, and delayed intracranial hemorrhage did not occur in this study. Mortality of octogenarians after a fall is most influenced by patient frailty. Acknowledgment of frailty, risk of recurrent falls, and increased mortality should direct goals of care for geriatric trauma patients.

Entities:  

Keywords:  Anticoagulation; falls; frailty; geriatric trauma; traumatic brain injury

Year:  2019        PMID: 31191123      PMCID: PMC6541068          DOI: 10.1080/08998280.2018.1550468

Source DB:  PubMed          Journal:  Proc (Bayl Univ Med Cent)        ISSN: 0899-8280


  30 in total

1.  The impact of preinjury antiplatelet and anticoagulant pharmacotherapy on outcomes in elderly patients with hemorrhagic brain injury.

Authors:  Gerald R Fortuna; Eric W Mueller; Laura E James; Lori A Shutter; Karyn L Butler
Journal:  Surgery       Date:  2008-08-29       Impact factor: 3.982

Review 2.  Effectiveness of intervention programs in preventing falls: a systematic review of recent 10 years and meta-analysis.

Authors:  Myunghan Choi; Melvin Hector
Journal:  J Am Med Dir Assoc       Date:  2011-06-15       Impact factor: 4.669

3.  Age and the risk of warfarin-associated hemorrhage: the anticoagulation and risk factors in atrial fibrillation study.

Authors:  Margaret C Fang; Alan S Go; Elaine M Hylek; Yuchiao Chang; Lori E Henault; Nancy G Jensvold; Daniel E Singer
Journal:  J Am Geriatr Soc       Date:  2006-08       Impact factor: 5.562

4.  Advanced age and preinjury warfarin anticoagulation increase the risk of mortality after head trauma.

Authors:  Jan Franko; Karen J Kish; Brendan G O'Connell; Sujata Subramanian; James V Yuschak
Journal:  J Trauma       Date:  2006-07

5.  Delayed intracranial hemorrhage after blunt trauma: are patients on preinjury anticoagulants and prescription antiplatelet agents at risk?

Authors:  Kimberly A Peck; C Beth Sise; Steven R Shackford; Michael J Sise; Richard Y Calvo; Daniel I Sack; Sarah B Walker; Mark S Schechter
Journal:  J Trauma       Date:  2011-12

Review 6.  Traumatic brain injury in older adults: epidemiology, outcomes, and future implications.

Authors:  Hilaire J Thompson; Wayne C McCormick; Sarah H Kagan
Journal:  J Am Geriatr Soc       Date:  2006-10       Impact factor: 5.562

Review 7.  Effectiveness and implementation aspects of interventions for preventing falls in elderly people in long-term care facilities: a systematic review of RCTs.

Authors:  Jacques C Neyens; Jolanda C van Haastregt; Béatrice P Dijcks; Mark Martens; Wim J van den Heuvel; Luc P de Witte; Jos M Schols
Journal:  J Am Med Dir Assoc       Date:  2010-10-20       Impact factor: 4.669

8.  A global clinical measure of fitness and frailty in elderly people.

Authors:  Kenneth Rockwood; Xiaowei Song; Chris MacKnight; Howard Bergman; David B Hogan; Ian McDowell; Arnold Mitnitski
Journal:  CMAJ       Date:  2005-08-30       Impact factor: 8.262

9.  Traumatic brain injuries evaluated in U.S. emergency departments, 1992-1994.

Authors:  T E Jager; H B Weiss; J H Coben; P E Pepe
Journal:  Acad Emerg Med       Date:  2000-02       Impact factor: 3.451

10.  Traumatic brain injury in the elderly: increased mortality and worse functional outcome at discharge despite lower injury severity.

Authors:  Mark Susman; Stephen M DiRusso; Thomas Sullivan; Donald Risucci; Peter Nealon; Sara Cuff; Adil Haider; Deborah Benzil
Journal:  J Trauma       Date:  2002-08
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  4 in total

1.  Circulating Interleukin-6 (but Not Other Immune Mediators) Associates with Criteria for Fried's Frailty among Very Old Adults.

Authors:  Gilberto Santos Morais Junior; Diego Ignacio Valenzuela Perez; Audrey Cecília Tonet-Furioso; Lucy Gomes; Karla Helena Coelho Vilaça; Vicente Paulo Alves; Clayton Franco Moraes; Otávio Toledo Nóbrega
Journal:  J Aging Res       Date:  2020-11-04

2.  Anticoagulant Therapy for Frail Patients with Atrial Fibrillation.

Authors:  Hiroshi Hori; Takahiko Fukuchi; Hitoshi Sugawara
Journal:  Intern Med       Date:  2021-02-15       Impact factor: 1.271

Review 3.  Acute traumatic brain injury in frail patients: the next pandemic.

Authors:  Marta Baggiani; Angelo Guglielmi; Giuseppe Citerio
Journal:  Curr Opin Crit Care       Date:  2022-04-01       Impact factor: 3.687

4.  Association between mortality and frailty in emergency general surgery: a systematic review and meta-analysis.

Authors:  Christophe Alain Fehlmann; Dilan Patel; Jessica McCallum; Jeffrey Joseph Perry; Debra Eagles
Journal:  Eur J Trauma Emerg Surg       Date:  2021-01-09       Impact factor: 3.693

  4 in total

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