Literature DB >> 3118034

Linkage analysis of peripheral neurofibromatosis to DNA markers on chromosome 8.

S R Diehl1, M Boehnke, F S Collins, R P Erickson, I J Karolyi, L M Ploughman, M A Pericak-Vance, A S Aylsworth, A D Roses.   

Abstract

Linkage relationships of the gene for peripheral neurofibromatosis (NF) were assessed in a large American Caucasian pedigree using two DNA markers located on chromosome 8. Linkage to the thyroglobulin locus, located at 8q24, was excluded (lod less than or equal to -2.0) to 21 cM. Data obtained for the tissue plasminogen activator locus, located at 8p12, excluded linkage to 4 cM. These results exclude between 20 to 30% of chromosome 8 as a possible map location for the NF gene in this family. Comparison of the two DNA markers excluded their linkage to 0.5 cM.

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Year:  1987        PMID： 3118034      PMCID： PMC1050261          DOI： 10.1136/jmg.24.9.532

Source DB:  PubMed          Journal:  J Med Genet        ISSN： 0022-2593            Impact factor:   6.318


  8 in total

1.  Sequential tests for the detection of linkage.

Authors:  N E MORTON
Journal:  Am J Hum Genet       Date:  1955-09       Impact factor: 11.025

Review 2.  The mapping of human chromosomes.

Authors:  J H Renwick
Journal:  Annu Rev Genet       Date:  1971       Impact factor: 16.830

3.  Human tissue-type plasminogen activator gene located near chromosomal breakpoint in myeloproliferative disorder.

Authors:  T L Yang-Feng; G Opdenakker; G Volckaert; U Francke
Journal:  Am J Hum Genet       Date:  1986-07       Impact factor: 11.025

4.  A computer program for linkage analysis of general human pedigrees.

Authors:  J Ott
Journal:  Am J Hum Genet       Date:  1976-09       Impact factor: 11.025

5.  Juvenile chronic granulocytic leukemia in a patient with trisomy 8, neurofibromatosis, and prolonged Epstein-Barr virus infection.

Authors:  C G Palmer; A J Provisor; D D Weaver; M E Hodes; N Heerema
Journal:  J Pediatr       Date:  1983-06       Impact factor: 4.406

6.  Linkage studies in peripheral neurofibromatosis.

Authors:  M A Pericak-Vance; L H Yamaoka; J M Vance; A S Aylsworth; G O Rossenwasser; P C Gaskell; M J Alberts; W Y Hung; C Haynes; A D Roses
Journal:  J Med Genet       Date:  1987-09       Impact factor: 6.318

7.  The human thyroglobulin gene: a polymorphic marker localized distal to C-MYC on chromosome 8 band q24.

Authors:  F Baas; H Bikker; A Geurts van Kessel; R Melsert; P L Pearson; J J de Vijlder; G J van Ommen
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

8.  Assignment of tissue-type plasminogen activator to chromosome 8 in man and identification of a common restriction length polymorphism within the gene.

Authors:  F J Benham; N Spurr; S Povey; B T Brinton; P N Goodfellow; E Solomon; T J Harris
Journal:  Mol Biol Med       Date:  1984-08
  8 in total
  2 in total

1.  An exclusion map for Von Recklinghausen neurofibromatosis.

Authors:  M Sarfarazi; S M Huson; J H Edwards
Journal:  J Med Genet       Date:  1987-09       Impact factor: 6.318

2.  A refined genetic map of the region of chromosome 17 surrounding the von Recklinghausen neurofibromatosis (NF1) gene.

Authors:  S R Diehl; M Boehnke; R P Erickson; L M Ploughman; K A Seiler; J L Lieberman; H B Clarke; M A Bruce; E K Schorry; M Pericak-Vance
Journal:  Am J Hum Genet       Date:  1989-01       Impact factor: 11.025
  2 in total

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