Literature DB >> 31170671

Novel design of low modulus high strength zirconia scaffolds for biomedical applications.

Ana Marques1, Georgina Miranda2, Diana Faria2, Paulo Pinto2, Filipe Silva2, Óscar Carvalho2.   

Abstract

This study intends to develop a novel zirconia scaffold design with a significantly lower Young's Modulus than zirconia bulk material (210 GPa) aiming to match this elastic property with that of the host bone, for application as endosseous implants. This scaffold with a complex interconnected structure can allow bone ingrowth, vascularization and provide a good initial stability. This novel thin-walled zirconia scaffold was manufactured by green machining and afterwards furnace sintered. The obtained YM of this zirconia scaffold was found significantly lower than zirconia bulk material due a less stiff geometry with small (walls and floors) dimensions. Insertion replication tests were performed for evaluating the fixation at the initial moment of implantation, being experimentally verified a high static initial coefficient of friction. The capillarity of these scaffolds was also assessed, revealing a very high rising speed of water inside these structures. This study proved that this novel ceramic scaffold design can be fabricated for several dimensions for obtaining desired elastic properties. The proposed fabrication strategy allows the fabrication of thin-walled structures unachievable by conventional machining.
Copyright © 2019 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Capillarity; Green machining; Implants; Scaffolds; Young's modulus; Zirconia

Year:  2019        PMID: 31170671     DOI: 10.1016/j.jmbbm.2019.05.005

Source DB:  PubMed          Journal:  J Mech Behav Biomed Mater        ISSN: 1878-0180


  3 in total

Review 1.  Characterisation of Selected Materials in Medical Applications.

Authors:  Kacper Kroczek; Paweł Turek; Damian Mazur; Jacek Szczygielski; Damian Filip; Robert Brodowski; Krzysztof Balawender; Łukasz Przeszłowski; Bogumił Lewandowski; Stanisław Orkisz; Artur Mazur; Grzegorz Budzik; Józef Cebulski; Mariusz Oleksy
Journal:  Polymers (Basel)       Date:  2022-04-09       Impact factor: 4.967

Review 2.  Customized Root-Analogue Implants: A Review on Outcomes from Clinical Trials and Case Reports.

Authors:  Telma Dantas; Sara Madeira; Michael Gasik; Paula Vaz; Filipe Silva
Journal:  Materials (Basel)       Date:  2021-04-29       Impact factor: 3.623

3.  Study on mechanical properties and permeability of elliptical porous scaffold based on the SLM manufactured medical Ti6Al4V.

Authors:  Chenglong Shi; Nana Lu; Yaru Qin; Mingdi Liu; Hongxia Li; Haichao Li
Journal:  PLoS One       Date:  2021-03-04       Impact factor: 3.240

  3 in total

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