| Literature DB >> 31167118 |
Curtis C Hughey1, Peter A Crawford2.
Abstract
Pyruvate carboxylase-mediated anaplerosis is a well-known regulator of gluconeogenesis. In this issue of Cell Metabolism, Cappel et al. (2019) show that pyruvate carboxylase action has far-reaching roles in metabolic homeostasis as it integrates glucose metabolism with tricarboxylic acid cycle flux, ureagenesis, redox potential, and defense against oxidative stress.Entities:
Mesh：
Substances：
Year: 2019 PMID： 31167118 DOI： 10.1016/j.cmet.2019.05.013
Source DB: PubMed Journal: Cell Metab ISSN： 1550-4131 Impact factor: 27.287