Literature DB >> 31165400

Do Non-participants at Screening have a Different Threshold for an Acceptable Benefit-Harm Ratio than Participants? Results of a Discrete Choice Experiment.

Tina Birgitte Hansen1,2, Jes Sanddal Lindholt3,4, Axel Diederichsen4,5, Rikke Søgaard6,7.   

Abstract

OBJECTIVE: The objective of the study was to investigate non-participants' preferences for cardiovascular disease screening programme characteristics and whether non-participation can be rationally explained by differences in preferences, decision-making styles and informational needs between non-participants and participants.
METHODS: We conducted a discrete choice experiment at three screening sites between June and December 2017 among 371 male non-participants and 830 male participants who were asked to trade different levels of five key programme characteristics (chance of health benefit, risk of overtreatment, risk of later regret, screening duration and screening location). Data were analysed using a multinomial mixed-logit model. Health benefit was used as a payment vehicle for estimation of marginal substitution rates.
RESULTS: Non-participants were willing to accept that 0.127 (95% confidence interval 0.103-0.154) fewer lives would be saved to avoid overtreatment of one individual, whilst participants were willing to accept 0.085 (95% confidence interval 0.077-0.094) fewer lives saved. This translates into non-participants valuing health benefits 7.9 times higher than overtreatment. The corresponding value of participants is 11.8. Similarly, non-participants had higher requirements than participants for advanced technology and a quicker screening duration. With regard to their participation decision, 64% of the non-participants felt certain about their choice compared with 89% among participants.
CONCLUSIONS: This study shows that non-participants have different preferences than participants at screening as they express relatively more concern about overtreatment and have higher requirements for a high-tech screening programme. Non-participants also report to be more uncertain about their participation decision and more often seek additional information to the standard information provided in the invitation letter. Further studies on informational needs and effective communication strategies are warranted to ensure that non-participation is a fully informed choice.

Entities:  

Year:  2019        PMID: 31165400     DOI: 10.1007/s40271-019-00364-z

Source DB:  PubMed          Journal:  Patient        ISSN: 1178-1653            Impact factor:   3.883


  36 in total

1.  Adherence to Prescribed Drugs Among 65-74 Year Old Men Diagnosed with Abdominal Aortic Aneurysm or Peripheral Arterial Disease in a Screening Trial: A VIVA Substudy.

Authors:  Ina Qvist; Rikke Søgaard; Jes S Lindholt; Vibeke Lorentzen; Jesper Hallas; Lars Frost
Journal:  Eur J Vasc Endovasc Surg       Date:  2018-11-02       Impact factor: 7.069

2.  Conjoint analysis applications in health--a checklist: a report of the ISPOR Good Research Practices for Conjoint Analysis Task Force.

Authors:  John F P Bridges; A Brett Hauber; Deborah Marshall; Andrew Lloyd; Lisa A Prosser; Dean A Regier; F Reed Johnson; Josephine Mauskopf
Journal:  Value Health       Date:  2011-04-22       Impact factor: 5.725

3.  Reasons for non-participation in population-based abdominal aortic aneurysm screening.

Authors:  A Linne; K Leander; D Lindström; S Törnberg; R Hultgren
Journal:  Br J Surg       Date:  2014-02-26       Impact factor: 6.939

4.  Population screening for coronary artery calcification does not increase mental distress and the use of psychoactive medication.

Authors:  Anders Daldorph Nielsen; Poul Videbech; Oke Gerke; Henrik Petersen; Jesper Møller Jensen; Niels Peter Rønnow Sand; Kenneth Egstrup; Mogens Lytken Larsen; Hans Mickley; Axel Cosmus Pyndt Diederichsen
Journal:  J Thorac Imaging       Date:  2012-05       Impact factor: 3.000

Review 5.  Personalised risk communication for informed decision making about taking screening tests.

Authors:  Adrian G K Edwards; Gurudutt Naik; Harry Ahmed; Glyn J Elwyn; Timothy Pickles; Kerry Hood; Rebecca Playle
Journal:  Cochrane Database Syst Rev       Date:  2013-02-28

6.  Cost-effectiveness of Screening for Abdominal Aortic Aneurysm in Combination with Medical Intervention in Patients with Small Aneurysms.

Authors:  M Zarrouk; A Lundqvist; J Holst; T Troëng; A Gottsäter
Journal:  Eur J Vasc Endovasc Surg       Date:  2016-03-05       Impact factor: 7.069

7.  The Viborg Vascular (VIVA) screening trial of 65-74 year old men in the central region of Denmark: study protocol.

Authors:  Nikolaj Grøndal; Rikke Søgaard; Eskild W Henneberg; Jes S Lindholt
Journal:  Trials       Date:  2010-05-27       Impact factor: 2.279

8.  Colorectal Cancer Screening: Preferences, Past Behavior, and Future Intentions.

Authors:  Carol Mansfield; Donatus U Ekwueme; Florence K L Tangka; Derek S Brown; Judith Lee Smith; Gery P Guy; Chunyu Li; Brett Hauber
Journal:  Patient       Date:  2018-12       Impact factor: 3.883

Review 9.  Common methods of measuring 'informed choice' in screening participation: Challenges and future directions.

Authors:  Alex Ghanouni; Cristina Renzi; Susanne F Meisel; Jo Waller
Journal:  Prev Med Rep       Date:  2016-10-28

10.  The NHS Health Check in England: an evaluation of the first 4 years.

Authors:  John Robson; Isabel Dostal; Aziz Sheikh; Sandra Eldridge; Vichithranie Madurasinghe; Chris Griffiths; Carol Coupland; Julia Hippisley-Cox
Journal:  BMJ Open       Date:  2016-01-13       Impact factor: 2.692

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  1 in total

Review 1.  Methodology to derive preference for health screening programmes using discrete choice experiments: a scoping review.

Authors:  David Brain; Amarzaya Jadambaa; Sanjeewa Kularatna
Journal:  BMC Health Serv Res       Date:  2022-08-24       Impact factor: 2.908

  1 in total

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