Literature DB >> 31161808

Distal Digital Nerve Repair Using Nerve Allograft With a Dermal Substitute: A Case Report.

Desirae McKee1, Bradley Osemwengie1, Cameron Cox1.   

Abstract

Background: Distal digital nerve repairs can present unique challenges for hand surgeons due to their sensitive location and ongoing difficulty obtaining soft tissue coverage in this region. Although autografts and nerve conduits have been shown to be of benefit with nerve gaps, they can have morbidities associated with their use. Nerve allografts have become a viable option over the past decade as their use has increased and data are now showing similar outcomes, particularly in short gap segments. Flaps and skin grafts are traditional coverage options for full thickness wounds but can pose challenges with multiple digit involvement, depth of wound, and critical structures exposed.
Methods: We present a case where nerve allograft was used for distal digital nerve repair. Due to the distal nature of the nerve repair in the index digit distal to the trifurcation, the distal end of the nerve graft was connected to multiple small nerve ends. Dermal substitute was placed to achieve distal coverage of the affected digits.
Results: At 6-month follow-up, the patient demonstrated improved strength, normal sensation, and full return of digital function.
Conclusion: Nerve allograft can be used in combination with dermal skin substitute to achieve normal sensation and return of digital function following distal digital nerve injuries.

Entities:  

Keywords:  allograft; anatomy; basic science; composite tissue allotransplantation; dermal substitute; diagnosis; digital nerve; digits; distal nerve injury; nerve; nerve allograft; nerve reconstruction; nerve repair; soft tissue reconstruction; trauma

Year:  2019        PMID: 31161808      PMCID: PMC7370397          DOI: 10.1177/1558944719854169

Source DB:  PubMed          Journal:  Hand (N Y)        ISSN: 1558-9447


  10 in total

Review 1.  Functional resurfacing of the palm: flap selection based on defect analysis.

Authors:  T O Engelhardt; U M Rieger; A H Schwabegger; G Pierer
Journal:  Microsurgery       Date:  2011-11-28       Impact factor: 2.425

2.  Nerve endoneurial microstructure facilitates uniform distribution of regenerative fibers: a post hoc comparison of midgraft nerve fiber densities.

Authors:  Philip J Johnson; Piyaraj Newton; Daniel A Hunter; Susan E Mackinnon
Journal:  J Reconstr Microsurg       Date:  2010-10-13       Impact factor: 2.873

3.  A Multicenter, Prospective, Randomized, Pilot Study of Outcomes for Digital Nerve Repair in the Hand Using Hollow Conduit Compared With Processed Allograft Nerve.

Authors:  Kenneth R Means; Brian D Rinker; James P Higgins; S Houston Payne; Gregory A Merrell; E F Shaw Wilgis
Journal:  Hand (N Y)       Date:  2016-02-17

4.  Allograft reconstruction for digital nerve loss.

Authors:  John S Taras; Nirav Amin; Nimit Patel; Lucy A McCabe
Journal:  J Hand Surg Am       Date:  2013-08-30       Impact factor: 2.230

5.  Outcomes of short-gap sensory nerve injuries reconstructed with processed nerve allografts from a multicenter registry study.

Authors:  Brian D Rinker; John V Ingari; Jeffrey A Greenberg; Wesley P Thayer; Bauback Safa; Gregory M Buncke
Journal:  J Reconstr Microsurg       Date:  2015-04-20       Impact factor: 2.873

6.  Integra® dermal regenerative template application on exposed tendon.

Authors:  John Hulsen; Ryan Diederich; Michael W Neumeister; Reuben A Bueno
Journal:  Hand (N Y)       Date:  2014-12

7.  Causes and consequences of hand injuries.

Authors:  Marek Trybus; Jacek Lorkowski; Leszek Brongel; Waldemar Hladki
Journal:  Am J Surg       Date:  2006-07       Impact factor: 2.565

Review 8.  A 25-year perspective of peripheral nerve surgery: evolving neuroscientific concepts and clinical significance.

Authors:  G Lundborg
Journal:  J Hand Surg Am       Date:  2000-05       Impact factor: 2.230

9.  Bioartificial dermal substitute: a preliminary report on its use for the management of complex combat-related soft tissue wounds.

Authors:  Melvin D Helgeson; Benjamin K Potter; Korboi N Evans; Scott B Shawen
Journal:  J Orthop Trauma       Date:  2007-07       Impact factor: 2.512

10.  Early clinical outcomes with the use of decellularized nerve allograft for repair of sensory defects within the hand.

Authors:  Furkan E Karabekmez; Ahmet Duymaz; Steven L Moran
Journal:  Hand (N Y)       Date:  2009-05-02
  10 in total

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