Literature DB >> 31158831

Technical note: MLC-tracking performance on the Elekta unity MRI-linac.

M Glitzner1, P L Woodhead, P T S Borman, J J W Lagendijk, B W Raaymakers.   

Abstract

Recently, multileaf collimator (MLC)-tracking has been technically and clinically demonstrated showing promising improvements of radiotherapy of mobile sites. Furthermore, magnetic resonance imaging (MRI)-guided treatments have shown to provide superior targetting performance due to on-line soft-tissue imaging. Hitherto, the combination of MLC-tracking and MRI has not been investigated using clinically released hardware. In this note we aim to describe the technical feasibilty of such a combination on a clinically operating MRI-linac. The MLC-tracking system is characterized by quantifying the latencies and geometric errors produced by the system. In order to reach optimization recommendations, the tracking system was first characterized using a quasi-ideal position sensor, isolating the performance of the MLC only. Subsequently, the analysis was repeated using real-time MRI as the positioning source for the MLC. For the isolated MLC, we found latencies of 20.67 ms and minimal overshooting behaviour. The latencies for MRI-guidance were 347.45 ms at 4 Hz imaging and 204 ms at 8 Hz. We showed that MLC-tracking on the Elekta Unity using integrated MRI is technically supported and feasible. The isolated analysis of the MLC demonstrated the negligible contribution of the MLC in MRI-guided tracking. The latency and geometric errors caused by the sampling properties of MRI exceed the MLC-related errors by several factors. Most gain for real-time MRI-based adaptive radiotherapy can therefore be realized by optimizing and accelerating the MRI acquisition process.

Mesh:

Year:  2019        PMID: 31158831     DOI: 10.1088/1361-6560/ab2667

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  11 in total

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Journal:  Med Phys       Date:  2021-11-19       Impact factor: 4.071

Review 2.  The future of MRI in radiation therapy: Challenges and opportunities for the MR community.

Authors:  Rosie J Goodburn; Marielle E P Philippens; Thierry L Lefebvre; Aly Khalifa; Tom Bruijnen; Joshua N Freedman; David E J Waddington; Eyesha Younus; Eric Aliotta; Gabriele Meliadò; Teo Stanescu; Wajiha Bano; Ali Fatemi-Ardekani; Andreas Wetscherek; Uwe Oelfke; Nico van den Berg; Ralph P Mason; Petra J van Houdt; James M Balter; Oliver J Gurney-Champion
Journal:  Magn Reson Med       Date:  2022-09-21       Impact factor: 3.737

3.  Effect of intrafraction adaptation on PTV margins for MRI guided online adaptive radiotherapy for rectal cancer.

Authors:  Chavelli M Kensen; Tomas M Janssen; Anja Betgen; Lisa Wiersema; Femke P Peters; Peter Remeijer; Corrie A M Marijnen; Uulke A van der Heide
Journal:  Radiat Oncol       Date:  2022-06-21       Impact factor: 4.309

4.  MR SIGnature MAtching (MRSIGMA) with retrospective self-evaluation for real-time volumetric motion imaging.

Authors:  Nathanael Kim; Kathryn R Tringale; Christopher Crane; Neelam Tyagi; Ricardo Otazo
Journal:  Phys Med Biol       Date:  2021-10-26       Impact factor: 4.174

Review 5.  Integrated MRI-guided radiotherapy - opportunities and challenges.

Authors:  Paul J Keall; Caterina Brighi; Carri Glide-Hurst; Gary Liney; Paul Z Y Liu; Suzanne Lydiard; Chiara Paganelli; Trang Pham; Shanshan Shan; Alison C Tree; Uulke A van der Heide; David E J Waddington; Brendan Whelan
Journal:  Nat Rev Clin Oncol       Date:  2022-04-19       Impact factor: 65.011

Review 6.  MRI-guided Radiation Therapy: An Emerging Paradigm in Adaptive Radiation Oncology.

Authors:  Ricardo Otazo; Philippe Lambin; Jean-Philippe Pignol; Mark E Ladd; Heinz-Peter Schlemmer; Michael Baumann; Hedvig Hricak
Journal:  Radiology       Date:  2020-12-22       Impact factor: 11.105

Review 7.  MR-guided proton therapy: a review and a preview.

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Journal:  Radiat Oncol       Date:  2020-05-29       Impact factor: 3.481

8.  Automatic reconstruction of the delivered dose of the day using MR-linac treatment log files and online MR imaging.

Authors:  Martin J Menten; Jonathan K Mohajer; Rahul Nilawar; Jenny Bertholet; Alex Dunlop; Angela U Pathmanathan; Michel Moreau; Spencer Marshall; Andreas Wetscherek; Simeon Nill; Alison C Tree; Uwe Oelfke
Journal:  Radiother Oncol       Date:  2020-01-10       Impact factor: 6.280

9.  Patterns of practice for adaptive and real-time radiation therapy (POP-ART RT) part I: Intra-fraction breathing motion management.

Authors:  Gail Anastasi; Jenny Bertholet; Per Poulsen; Toon Roggen; Cristina Garibaldi; Nina Tilly; Jeremy T Booth; Uwe Oelfke; Ben Heijmen; Marianne C Aznar
Journal:  Radiother Oncol       Date:  2020-06-23       Impact factor: 6.280

Review 10.  Medical physics challenges in clinical MR-guided radiotherapy.

Authors:  Christopher Kurz; Giulia Buizza; Guillaume Landry; Florian Kamp; Moritz Rabe; Chiara Paganelli; Guido Baroni; Michael Reiner; Paul J Keall; Cornelis A T van den Berg; Marco Riboldi
Journal:  Radiat Oncol       Date:  2020-05-05       Impact factor: 3.481

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