Literature DB >> 31157251

Quality in practice: implementation of a clinical outcomes registry in regenerative medicine.

Frank Zackary Jenio1, Corey Scholes2, Maimuna Marenah3, Jinjie Li3, Mac Cowley2, Milad Ebrahimi2, Meredith Harrison-Brown2, William D Murrell3,4,5,6.   

Abstract

BACKGROUND: The aim of this didactic article is to describe the implementation of a clinical outcomes registry within a clinical setting for musculoskeletal regenerative medicine. A patient-centred clinical registry, designed and implemented into the practice of a musculoskeletal clinic specializing in regenerative medicine.
METHODS: A focus on patient outcomes at all levels of the patient journey was established to monitor and continually improve care. The registry was designed to monitor the diagnosis, treatment and outcomes of musculoskeletal pathologies of the shoulder, elbow, hip, knee, foot and spine presenting to the clinic. Specifically, the registry was designed for surveillance, tracking, and reporting of efficacy and adverse events of cellular-based therapies.
RESULTS: The registry has completed its implementation phase and is now in a pilot period to confirm data collection processes and user feedback. Initial findings indicate suboptimal data entry compliance in key areas that were rectified by refining data fields, reimaging within existing operating systems, and linkage to external supporting documents.
CONCLUSIONS: The key impacts of the registry implementation have been to (I) redefine criteria for treatment success and failure within the area of biologic treatments in musculoskeletal practice; (II) instigate discussion, and document standardized treatment pathways, clinical handover processes and shared decision-making with patients; and (III) act as a catalyst to target deficiencies in staff knowledge and skills in the areas of patient management and interaction, clinical documentation and administration processes. A practice registry provides a platform for monitoring treatment safety and efficacy in the context of biologic therapies in musculoskeletal medicine. Registries of this kind will contribute to ongoing discourse regarding best value treatments in the musculoskeletal context.

Entities:  

Keywords:  Clinical outcomes; quality; regenerative medicine; registry

Year:  2019        PMID: 31157251      PMCID: PMC6511570          DOI: 10.21037/atm.2019.02.38

Source DB:  PubMed          Journal:  Ann Transl Med        ISSN: 2305-5839


  17 in total

1.  How Intermountain trimmed health care costs through robust quality improvement efforts.

Authors:  Brent C James; Lucy A Savitz
Journal:  Health Aff (Millwood)       Date:  2011-05-19       Impact factor: 6.301

2.  Surgeon volume is associated with cost and variation in surgical treatment of proximal humeral fractures.

Authors:  Nitin B Jain; Ifedayo Kuye; Laurence D Higgins; Jon J P Warner
Journal:  Clin Orthop Relat Res       Date:  2012-07-24       Impact factor: 4.176

3.  Using patient-reported outcomes in routine practice: three novel use cases and implications.

Authors:  Helena Hvitfeldt Forsberg; Eugene C Nelson; Robert Reid; David Grossman; Melanie P Mastanduno; Lisa Torrey Weiss; Elliott S Fisher; James N Weinstein
Journal:  J Ambul Care Manage       Date:  2015 Apr-Jun

Review 4.  Regenerative treatments to enhance orthopedic surgical outcome.

Authors:  William D Murrell; Adam W Anz; Humeira Badsha; William F Bennett; Robert E Boykin; Arnold I Caplan
Journal:  PM R       Date:  2015-04       Impact factor: 2.298

5.  Safety and complications reporting update on the re-implantation of culture-expanded mesenchymal stem cells using autologous platelet lysate technique.

Authors:  Christopher J Centeno; John R Schultz; Michelle Cheever; Michael Freeman; Stephen Faulkner; Brent Robinson; Ronald Hanson
Journal:  Curr Stem Cell Res Ther       Date:  2011-12       Impact factor: 3.828

6.  National registries of systemic treatment for psoriasis and the European 'Psonet' initiative.

Authors:  L L A Lecluse; L Naldi; R S Stern; P I Spuls
Journal:  Dermatology       Date:  2008-12-11       Impact factor: 5.366

7.  The National Registry of Veterans with amyotrophic lateral sclerosis.

Authors:  K D Allen; E J Kasarskis; R S Bedlack; M P Rozear; J C Morgenlander; A Sabet; L Sams; J H Lindquist; M L Harrelson; C J Coffman; E Z Oddone
Journal:  Neuroepidemiology       Date:  2008-04-18       Impact factor: 3.282

8.  Quality in practice: implementation of hospital guidelines for patient identification in Malawi.

Authors:  Tom Latham; Olive Malomboza; Loveness Nyirenda; Paul Ashford; Jean Emmanuel; Bridon M'baya; Imelda Bates
Journal:  Int J Qual Health Care       Date:  2012-07-25       Impact factor: 2.038

9.  Quality in practice: integrating routine collection of patient language data into hospital practice.

Authors:  Patricia Hudelson; Melissa Dominicé Dao; Sophie Durieux-Paillard
Journal:  Int J Qual Health Care       Date:  2013-05-21       Impact factor: 2.038

10.  Patient-centered activity monitoring in the self-management of chronic health conditions.

Authors:  Emil Chiauzzi; Carlos Rodarte; Pronabesh DasMahapatra
Journal:  BMC Med       Date:  2015-04-09       Impact factor: 8.775

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