Literature DB >> 31156275

PEt3-Mediated Deoxygenative C-N Coupling of Nitroarenes and Boronic Acids.

Trevor V Nykaza1, Junyu Yang1, Alexander T Radosevich1.   

Abstract

A method for the preparation of aryl- and heteroarylamine products by triethylphosphine-mediated deoxygenative coupling of nitroarenes and boronic acids is reported. This method provides access to an array of functionalized (hetero)arylamine products from readily available starting materials under the action of an inexpensive commercial reagent. The developed triethylphosphine-mediated transformation highlights the capability of organophosphorus compounds to carry out this useful deoxygenative transformation without the necessity of any transition metal additives.

Entities:  

Keywords:  Boronic Acid; C-N bond formation; Nitroarene; Phosphine

Year:  2019        PMID： 31156275      PMCID： PMC6541010          DOI： 10.1016/j.tet.2019.03.035

Source DB:  PubMed          Journal:  Tetrahedron        ISSN： 0040-4020            Impact factor:   2.457


  20 in total

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2.  An Improved PIII/PV═O-Catalyzed Reductive C-N Coupling of Nitroaromatics and Boronic Acids by Mechanistic Differentiation of Rate- and Product-Determining Steps.

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