Literature DB >> 31154041

Clinical Epidemiology of COPD: Insights From 10 Years of the COPDGene Study.

Diego J Maselli1, Surya P Bhatt2, Antonio Anzueto1, Russell P Bowler3, Dawn L DeMeo4, Alejandro A Diaz5, Mark T Dransfield2, Ashraf Fawzy6, Marilyn G Foreman7, Nicola A Hanania8, Craig P Hersh4, Victor Kim9, Gregory L Kinney10, Nirupama Putcha6, Emily S Wan11, J Michael Wells2, Gloria E Westney7, Kendra A Young10, Edwin K Silverman4, MeiLan K Han12, Barry J Make13.   

Abstract

The Genetic Epidemiology of COPD (COPDGene) study is a noninterventional, multicenter, longitudinal analysis of > 10,000 subjects, including smokers with a ≥ 10 pack-year history with and without COPD and healthy never smokers. The goal was to characterize disease-related phenotypes and explore associations with susceptibility genes. The subjects were extensively phenotyped with the use of comprehensive symptom and comorbidity questionnaires, spirometry, CT scans of the chest, and genetic and biomarker profiling. The objective of this review was to summarize the major advances in the clinical epidemiology of COPD from the first 10 years of the COPDGene study. We highlight the influence of age, sex, and race on the natural history of COPD, and the impact of comorbid conditions, chronic bronchitis, exacerbations, and asthma/COPD overlap.
Copyright © 2019. Published by Elsevier Inc.

Entities:  

Keywords:  COPD; COPDGene; chronic bronchitis; comorbidities; epidemiology; sex

Mesh：

Year:  2019        PMID： 31154041      PMCID： PMC7198872          DOI： 10.1016/j.chest.2019.04.135

Source DB:  PubMed          Journal:  Chest        ISSN： 0012-3692            Impact factor:   9.410


  45 in total

1.  Design of the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS).

Authors:  David Couper; Lisa M LaVange; MeiLan Han; R Graham Barr; Eugene Bleecker; Eric A Hoffman; Richard Kanner; Eric Kleerup; Fernando J Martinez; Prescott G Woodruff; Stephen Rennard
Journal:  Thorax       Date:  2013-09-12       Impact factor: 9.139

2.  Gender differences in COPD: are women more susceptible to smoking effects than men?

Authors:  Inga-Cecilie Sørheim; Ane Johannessen; Amund Gulsvik; Per S Bakke; Edwin K Silverman; Dawn L DeMeo
Journal:  Thorax       Date:  2010-06       Impact factor: 9.139

3.  Identification and prospective validation of clinically relevant chronic obstructive pulmonary disease (COPD) subtypes.

Authors:  Judith Garcia-Aymerich; Federico P Gómez; Marta Benet; Eva Farrero; Xavier Basagaña; Àngel Gayete; Carles Paré; Xavier Freixa; Jaume Ferrer; Antoni Ferrer; Josep Roca; Juan B Gáldiz; Jaume Sauleda; Eduard Monsó; Joaquim Gea; Joan A Barberà; Àlvar Agustí; Josep M Antó
Journal:  Thorax       Date:  2010-12-21       Impact factor: 9.139

4.  Reduced Bone Density and Vertebral Fractures in Smokers. Men and COPD Patients at Increased Risk.

Authors:  Joshua D Jaramillo; Carla Wilson; Douglas S Stinson; Douglas J Stinson; David A Lynch; Russell P Bowler; Sharon Lutz; Jessica M Bon; Ben Arnold; Merry-Lynn N McDonald; George R Washko; Emily S Wan; Dawn L DeMeo; Marilyn G Foreman; Xavier Soler; Sarah E Lindsay; Nancy E Lane; Harry K Genant; Edwin K Silverman; John E Hokanson; Barry J Make; James D Crapo; Elizabeth A Regan
Journal:  Ann Am Thorac Soc       Date:  2015-05

5.  The chronic bronchitic phenotype of COPD: an analysis of the COPDGene Study.

Authors:  Victor Kim; MeiLan K Han; Gwendolyn B Vance; Barry J Make; John D Newell; John E Hokanson; Craig P Hersh; Douglas Stinson; Edwin K Silverman; Gerard J Criner
Journal:  Chest       Date:  2011-04-07       Impact factor: 9.410

6.  Abdominal Visceral Adipose Tissue is Associated with Myocardial Infarction in Patients with COPD.

Authors:  Alejandro A Diaz; Tom P Young; Sila Kurugol; Erick Eckbo; Nina Muralidhar; Joshua K Chapman; Gregory L Kinney; James C Ross; Raul San Jose Estepar; Rola Harmouche; Jennifer L Black-Shinn; Matthew Budoff; Russell P Bowler; John Hokanson; George R Washko
Journal:  Chronic Obstr Pulm Dis       Date:  2015

7.  Early-onset chronic obstructive pulmonary disease is associated with female sex, maternal factors, and African American race in the COPDGene Study.

Authors:  Marilyn G Foreman; Lening Zhang; James Murphy; Nadia N Hansel; Barry Make; John E Hokanson; George Washko; Elizabeth A Regan; James D Crapo; Edwin K Silverman; Dawn L DeMeo
Journal:  Am J Respir Crit Care Med       Date:  2011-08-15       Impact factor: 21.405

8.  The clinical features of the overlap between COPD and asthma.

Authors:  Megan Hardin; Edwin K Silverman; R Graham Barr; Nadia N Hansel; Joyce D Schroeder; Barry J Make; James D Crapo; Craig P Hersh
Journal:  Respir Res       Date:  2011-09-27

9.  Functional and Prognostic Implications of the Main Pulmonary Artery Diameter to Aorta Diameter Ratio from Chest Computed Tomography in Korean COPD Patients.

Authors:  Kyung Soo Chung; Young Sam Kim; Se Kyu Kim; Ha Yan Kim; Sang Min Lee; Joon Beom Seo; Yeon Mok Oh; Ji Ye Jung; Sang-Do Lee
Journal:  PLoS One       Date:  2016-05-06       Impact factor: 3.240

10.  Pulmonary vascular pruning in smokers with bronchiectasis.

Authors:  Alejandro A Diaz; Diego J Maselli; Farbod Rahaghi; Carolyn E Come; Andrew Yen; Erick S Maclean; Yuka Okajima; Carlos H Martinez; Tsuneo Yamashiro; David A Lynch; Wei Wang; Gregory L Kinney; George R Washko; Raúl San José Estépar
Journal:  ERJ Open Res       Date:  2018-11-23
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  18 in total

Review 1.  Machine Learning Characterization of COPD Subtypes: Insights From the COPDGene Study.

Authors:  Peter J Castaldi; Adel Boueiz; Jeong Yun; Raul San Jose Estepar; James C Ross; George Washko; Michael H Cho; Craig P Hersh; Gregory L Kinney; Kendra A Young; Elizabeth A Regan; David A Lynch; Gerald J Criner; Jennifer G Dy; Stephen I Rennard; Richard Casaburi; Barry J Make; James Crapo; Edwin K Silverman; John E Hokanson
Journal:  Chest       Date:  2019-12-28       Impact factor: 9.410

Review 2.  Pathogenesis of chronic obstructive pulmonary disease (COPD) induced by cigarette smoke.

Authors:  Mari Hikichi; Kenji Mizumura; Shuichiro Maruoka; Yasuhiro Gon
Journal:  J Thorac Dis       Date:  2019-10       Impact factor: 2.895

3.  10-Year Follow-Up of Lung Function, Respiratory Symptoms, and Functional Capacity in the COPDGene Study.

Authors:  Margaret F Ragland; Matthew Strand; David Baraghoshi; Kendra A Young; Gregory L Kinney; Erin Austin; John E Hokanson; Elizabeth Regan; James Crapo; Edwin K Silverman; Barry Make
Journal:  Ann Am Thorac Soc       Date:  2022-03

4.  Protocol for a feasibility randomized trial of self-management support for people with chronic obstructive pulmonary disease using lay health coaches.

Authors:  Alex D Federman; Michele Barry; Esther Moas; Claire Davenport; Christina McGeough; Marisilis Tejeda; Leny Rivera; Stacie Gutierrez; Hilda Mejias; Destini Belton; Cathleen Mathew; Peter K Lindenauer; Danielle McDermott; Rachel O'Conor; Michael S Wolf; Juan P Wisnivesky
Journal:  Contemp Clin Trials       Date:  2021-09-21       Impact factor: 2.226

5.  Chronic Bronchitis in COPD Patients Creates Worse Symptom Burden Regardless of the Presence of Bronchiectasis in the COPDGene Cohort.

Authors:  Oksana Bohn; Min Xi; Natalie K Woodruff; Gary L Hansen; Charlene E McEvoy
Journal:  Chronic Obstr Pulm Dis       Date:  2021-07-28

6.  Blood RNA sequencing shows overlapping gene expression across COPD phenotype domains.

Authors:  Auyon J Ghosh; Aabida Saferali; Sool Lee; Robert Chase; Matthew Moll; Jarrett Morrow; Jeong Yun; Peter J Castaldi; Craig P Hersh
Journal:  Thorax       Date:  2021-06-24       Impact factor: 9.139

Review 7.  CT Imaging and Comorbidities in COPD: Beyond Lung Cancer Screening.

Authors:  Deepti Singhvi; Jessica Bon
Journal:  Chest       Date:  2020-08-22       Impact factor: 9.410

8.  Classification of COPD patients and compliance to recommended treatment in Greece according to GOLD 2017 report: the RELICO study.

Authors:  Nikolaos Tzanakis; Nikolaos Koulouris; Katerina Dimakou; Konstantinos Gourgoulianis; Epameinondas Kosmas; Georgia Chasapidou; Athanasios Konstantinidis; Christos Kyriakopoulos; Theodoros Kontakiotis; Aggeliki Rapti; Mina Gaga; Konstantinos Kalafatakis; Konstantinos Kostikas
Journal:  BMC Pulm Med       Date:  2021-07-09       Impact factor: 3.317

9.  MiR-221-3p and miR-92a-3p enhances smoking-induced inflammation in COPD.

Authors:  Yahui Shen; Huiyu Lu; Guixian Song
Journal:  J Clin Lab Anal       Date:  2021-06-07       Impact factor: 2.352

10.  Distribution of COPD Comorbidities and Creation of Acute Exacerbation Risk Score: Results from SCICP.

Authors:  Haiyan Ge; Xuanqi Liu; Wenchao Gu; Xiumin Feng; Fengying Zhang; Fengfeng Han; Yechang Qian; Xiaoyan Jin; Beilan Gao; Li Yu; Hong Bao; Min Zhou; Shengqing Li; Zhijun Jie; Jian Wang; Zhihong Chen; Jingqing Hang; Jingxi Zhang; Huili Zhu
Journal:  J Inflamm Res       Date:  2021-07-15
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