O Yilmaz1, V Mevsim2, E Kuruoglu3. 1. Arpaçay Family Health Center, Kars, "Dokuz Eylul" University Faculty of Medicine, Izmir, Turkey. 2. Family Medicine, Izmir, Turkey. 3. Computer Science, Izmir, Turkey.
Abstract
CONTEXT: DEXA is recommended for osteoporosis screening. However, the rate of screening with DEXA is very low. Therefore, methods that can be used more easily and cost effectively are needed. OBJECTIVE: The objective of this study is to develop a clinical risk assessment tool of osteoporosis (OSTEORISKAPP) by using syndromic approach. DESIGN: A methodological study was performed. SUBJECTS AND METHODS: Three hundred and fifty-six participants who are above 50 years old are participants of study and take history and physical examination. Positive likelihood ratio (LR), pre and post test probability, is calculated. A logistic regression analysis and a ROC analysis are made with the model constructed by those criteria. RESULTS: Eighteen different clinical risk indices are diagnosed. According to LR, 4 of these criteria are minimally effective, 11 of them are weakly effective and 3 of them are medium effective criteria According to results of logistic regression analysis, back pain, waist pain, and usage of cortisone for more than 3 months, vertebra tenderness in physical examination, having dorsal kyphosis and being obese are turned out to be statistically significant in 89.9% confidence interval. AUC is found to be 0.948 and diagnostic test is found to have perfect distinction ability. CONCLUSION: Syndromic diagnostic criteria that will be used for osteoporosis screening of population and that is cost effective, no need to refer, practical, reliable and has tried to be developed.
CONTEXT: DEXA is recommended for osteoporosis screening. However, the rate of screening with DEXA is very low. Therefore, methods that can be used more easily and cost effectively are needed. OBJECTIVE: The objective of this study is to develop a clinical risk assessment tool of osteoporosis (OSTEORISKAPP) by using syndromic approach. DESIGN: A methodological study was performed. SUBJECTS AND METHODS: Three hundred and fifty-six participants who are above 50 years old are participants of study and take history and physical examination. Positive likelihood ratio (LR), pre and post test probability, is calculated. A logistic regression analysis and a ROC analysis are made with the model constructed by those criteria. RESULTS: Eighteen different clinical risk indices are diagnosed. According to LR, 4 of these criteria are minimally effective, 11 of them are weakly effective and 3 of them are medium effective criteria According to results of logistic regression analysis, back pain, waist pain, and usage of cortisone for more than 3 months, vertebra tenderness in physical examination, having dorsal kyphosis and being obese are turned out to be statistically significant in 89.9% confidence interval. AUC is found to be 0.948 and diagnostic test is found to have perfect distinction ability. CONCLUSION: Syndromic diagnostic criteria that will be used for osteoporosis screening of population and that is cost effective, no need to refer, practical, reliable and has tried to be developed.
Authors: Suzanne M Cadarette; Warren J McIsaac; Gillian A Hawker; Liisa Jaakkimainen; Alison Culbert; Gihane Zarifa; Ebele Ola; Susan B Jaglal Journal: Osteoporos Int Date: 2004-01-17 Impact factor: 4.507
Authors: A R Negru; C Tiliscan; A M Tudor; D I Munteanu; C Popescu; M Lazar; A Streinu-Cercel; V Arama; S S Arama Journal: Acta Endocrinol (Buchar) Date: 2019 Oct-Dec Impact factor: 0.877