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Literature DB >> 31141

Gamma glutamyl transpeptidase levels in arthritis: a correlation with clinical and laboratory indices of disease activity.

J R Lowe, M E Pickup, J S Dixon, P A Leatham, V M Rhind, V Wright, W W Downie.

Abstract

Gamma glutamyl transpeptidase (GGTP) was measured in 62 patients with rheumatoid arthritis (RA) and 27 with osteoarthrosis (OA). The values for GGTP were significantly higher in the subjects with RA compared with the OA group. The prevalence of elevation of GGTP was higher in the RA subjects (77%) than in the OA patients (33%). Levels of GGTP correlated significantly with a number of objective indices of activity of RA in a separate group of 28 patients. Following treatment with penicillamine, GGTP levels showed a significant drop towards normal levels.

Entities: Chemical Disease Gene Species

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Year: 1978 PMID： 31141 PMCID： PMC1000270 DOI： 10.1136/ard.37.5.428

Source DB: PubMed Journal: Ann Rheum Dis ISSN： 0003-4967 Impact factor: 19.103

14 in total

1. The influence of drugs and disease activity on biochemical and haematological data in rheumatoid arthritis.

Authors: P Wilding; M J Kendall; R Holder; J A Grimes; M Farr
Journal: Clin Chim Acta Date: 1975-10-15 Impact factor: 3.786

2. A gel diffusion precipitin method for the estimation of C-reactive protein.

Authors: R A CROCKSON
Journal: J Clin Pathol Date: 1963-05 Impact factor: 3.411

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Authors:
Journal: Arthritis Rheum Date: 1959-02

Review 4. Gamma-glutamyl transpeptidase.

Authors: S B Rosalki
Journal: Adv Clin Chem Date: 1975 Impact factor: 5.394

5. Liver disease in patients with joint symptoms.

Authors: A M Hilton; B E Boyes; P J Smith; J Sharp; I W Dymock
Journal: Ann Rheum Dis Date: 1974-11 Impact factor: 19.103

6. Clinical studies with an articular index for the assessment of joint tenderness in patients with rheumatoid arthritis.

Authors: D M Ritchie; J A Boyle; J M McInnes; M K Jasani; T G Dalakos; P Grieveson; W W Buchanan
Journal: Q J Med Date: 1968-07

7. Liver disease in rheumatoid arthritis and Sjøgren's syndrome. Prospective study using biochemical and serological markers of hepatic dysfunction.

Authors: J Webb; K Whaley; R N MacSween; G Nuki; W C Dick; W W Buchanan
Journal: Ann Rheum Dis Date: 1975-02 Impact factor: 19.103

Review 8. The viscosity of human blood plasma; its measurement in health and disease.

Authors: J Harkness
Journal: Biorheology Date: 1971-12 Impact factor: 1.875

9. ESTIMATION OF SERUM HAEMOGLOBIN-BINDING CAPACITY (HAPTOGLOBIN) ON SEPHADEX G.100.

Authors: A P RATCLIFF; J HARDWICKE
Journal: J Clin Pathol Date: 1964-11 Impact factor: 3.411

10. Changes in plasma -glutamyl transpeptidase activity associated with alterations in drug metabolism in man.

Authors: J B Whitfield; D W Moss; G Neale; M Orme; A Breckenridge
Journal: Br Med J Date: 1973-02-10

7 in total

1. Influence of non-steroidal anti-inflammatory drugs and disease activity on serum alkaline phosphatase concentrations in rheumatoid arthritis, osteoarthritis, and polymyalgia rheumatica.

Authors: A Doube; J Davies; M Davis; P J Maddison
Journal: Ann Rheum Dis Date: 1989-05 Impact factor: 19.103

Gamma glutamyl transpeptidase levels in arthritis: a correlation with clinical and laboratory indices of disease activity.

1. The influence of drugs and disease activity on biochemical and haematological data in rheumatoid arthritis.

2. A gel diffusion precipitin method for the estimation of C-reactive protein.

3. 1958 REVISION of diagnostic criteria for rheumatoid arthritis.

Review 4. Gamma-glutamyl transpeptidase.

5. Liver disease in patients with joint symptoms.

6. Clinical studies with an articular index for the assessment of joint tenderness in patients with rheumatoid arthritis.

7. Liver disease in rheumatoid arthritis and Sjøgren's syndrome. Prospective study using biochemical and serological markers of hepatic dysfunction.

Review 8. The viscosity of human blood plasma; its measurement in health and disease.

9. ESTIMATION OF SERUM HAEMOGLOBIN-BINDING CAPACITY (HAPTOGLOBIN) ON SEPHADEX G.100.

10. Changes in plasma -glutamyl transpeptidase activity associated with alterations in drug metabolism in man.

1. Influence of non-steroidal anti-inflammatory drugs and disease activity on serum alkaline phosphatase concentrations in rheumatoid arthritis, osteoarthritis, and polymyalgia rheumatica.

2. Is serum gamma-glutamyltransferase a misleading test?

3. Involvement of the liver in rheumatic diseases.

4. Serum gamma-glutamyltransferase and alkaline phosphatase in rheumatoid arthritis.

5. Discriminatory indices of response of patients with rheumatoid arthritis treated with D-penicillamine.

6. Alcohol consumption in arthritic patients: clinical and laboratory studies.

Review 7. Gastrointestinal and hepatic manifestations of rheumatoid arthritis.