Literature DB >> 3113520

A monoclonal antibody to the heavy chain of human IgM with a particular reaction pattern in human B-cell malignancies.

M Henke, S Santos, C D Winberg, J E Shively.   

Abstract

We produced a monoclonal antibody to the human mu-chain. Its specificity was proved by amino acid-sequence analysis of immunoabsorbent purified cell surface antigen. In binding studies an affinity constant (K-aff) of 5.7 X 10(9) M-1 was determined. When compared with a polyclonal anti-IgM antiserum it was found that this antibody may react with a determinant of the mu-chain differently exposed in clonal B-cell disorders rendering it to a reagent of particular diagnostic interest.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 3113520     DOI： 10.1007/bf00320573

Source DB:  PubMed          Journal:  Blut        ISSN： 0006-5242


  24 in total

1.  Isolation of pure IgG1, IgG2a and IgG2b immunoglobulins from mouse serum using protein A-sepharose.

Authors:  P L Ey; S J Prowse; C R Jenkin
Journal:  Immunochemistry       Date:  1978-07

2.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

3.  Early production of intracellular IgM by B-lymphocyte precursors in mouse.

Authors:  M C Raff; M Megson; J J Owen; M D Cooper
Journal:  Nature       Date:  1976-01-22       Impact factor: 49.962

4.  A monoclonal antibody to hemoglobin F.

Authors:  H Muensch; T Hecht; K J Winkler; L Gaidulis; M Henke; K G Blume
Journal:  Blut       Date:  1984-09

5.  Phenotypes in chronic B-lymphocytic leukemia probed by monoclonal antibodies and immunoglobulin secretion studies: identification of stages of maturation arrest and the relation to clinical findings.

Authors:  J Gordon; H Mellstedt; P Aman; P Biberfeld; M Björkholm; G Klein
Journal:  Blood       Date:  1983-10       Impact factor: 22.113

6.  A better cell line for making hybridomas secreting specific antibodies.

Authors:  M Shulman; C D Wilde; G Köhler
Journal:  Nature       Date:  1978-11-16       Impact factor: 49.962

7.  Coincidence of B-cell chronic lymphocytic leukemia and cutaneous T-cell lymphoma (mycosis fungoides): immunologic characterization by monoclonal antibodies.

Authors:  K Sheibani; S J Forman; C D Winberg; H Rappaport
Journal:  Blood       Date:  1983-12       Impact factor: 22.113

8.  Pre-B cell leukemia responds poorly to treatment: a pediatric oncology group study.

Authors:  W Crist; J Boyett; M Roper; J Pullen; R Metzgar; J van Eys; A Ragab; K Starling; T Vietti; M Cooper
Journal:  Blood       Date:  1984-02       Impact factor: 22.113

9.  A highly conserved determinant on human rheumatoid factor idiotypes defined by a mouse monoclonal antibody.

Authors:  J L Pasquali; A Urlacher; D Storck
Journal:  Eur J Immunol       Date:  1983-03       Impact factor: 5.532

10.  Terminal deoxynucleotidyl transferase activity in neoplastic and nonneoplastic hematopoietic cells.

Authors:  R M Bearman; C D Winberg; W C Maslow; B Racklin; F Carlson; B N Nathwani; H Kim; L W Diamond; B Fallis; H Rappaport
Journal:  Am J Clin Pathol       Date:  1981-06       Impact factor: 2.493
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.