Literature DB >> 3113463

Activity of interferons alpha, beta, and gamma against human immunodeficiency virus replication in vitro.

K L Hartshorn, D Neumeyer, M W Vogt, R T Schooley, M S Hirsch.   

Abstract

The antiviral activities of various interferon preparations against human immunodeficiency virus (HIV) were evaluated in vitro. Recombinant interferon alpha-A, and beta interferons and leukocyte-derived alpha interferons show similar concentration-dependent antiviral activity. Recombinant and lymphocyte-derived gamma interferons show minimal antiviral activity against HIV replication in normal peripheral blood mononuclear cells, but definite activity against HIV in the H9 lymphocytic and U937 monocyte-macrophage cell lines.

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Year:  1987        PMID： 3113463     DOI： 10.1089/aid.1987.3.125

Source DB:  PubMed          Journal:  AIDS Res Hum Retroviruses        ISSN： 0889-2229            Impact factor:   2.205


  33 in total

1.  Progression of Kaposi's sarcoma under a combined interferon beta and interferon gamma therapy in AIDS patients.

Authors:  N H Brockmeyer; L Mertins; M Goos
Journal:  Klin Wochenschr       Date:  1990-12-17

2.  Novel function of prothymosin alpha as a potent inhibitor of human immunodeficiency virus type 1 gene expression in primary macrophages.

Authors:  Arevik Mosoian; Avelino Teixeira; Anthony A High; Robert E Christian; Donald F Hunt; Jeffrey Shabanowitz; Xinyan Liu; Mary Klotman
Journal:  J Virol       Date:  2006-09       Impact factor: 5.103

3.  A soluble factor(s) secreted from CD8(+) T lymphocytes inhibits human immunodeficiency virus type 1 replication through STAT1 activation.

Authors:  Theresa Li-Yun Chang; Arevik Mosoian; Richard Pine; Mary E Klotman; John P Moore
Journal:  J Virol       Date:  2002-01       Impact factor: 5.103

4.  Construction and characterization of replication-competent simian immunodeficiency virus vectors that express gamma interferon.

Authors:  L D Giavedoni; T Yilma
Journal:  J Virol       Date:  1996-04       Impact factor: 5.103

5.  Selective inhibition of human immunodeficiency virus type 1 replication by the (-) but not the (+) enantiomer of gossypol.

Authors:  T S Lin; R Schinazi; B P Griffith; E M August; B F Eriksson; D K Zheng; L A Huang; W H Prusoff
Journal:  Antimicrob Agents Chemother       Date:  1989-12       Impact factor: 5.191

6.  Virion-Associated Vpr Alleviates a Postintegration Block to HIV-1 Infection of Dendritic Cells.

Authors:  Caitlin M Miller; Hisashi Akiyama; Luis M Agosto; Ann Emery; Chelsea R Ettinger; Ronald I Swanstrom; Andrew J Henderson; Suryaram Gummuluru
Journal:  J Virol       Date:  2017-06-09       Impact factor: 5.103

7.  Human immunodeficiency virus type 1-specific cytotoxic T lymphocytes release gamma interferon, tumor necrosis factor alpha (TNF-alpha), and TNF-beta when they encounter their target antigens.

Authors:  C Jassoy; T Harrer; T Rosenthal; B A Navia; J Worth; R P Johnson; B D Walker
Journal:  J Virol       Date:  1993-05       Impact factor: 5.103

8.  Evidence for a different susceptibility of primate lentiviruses to type I interferons.

Authors:  Stéphanie Cordeil; Xuan-Nhi Nguyen; Gregory Berger; Stéphanie Durand; Michelle Ainouze; Andrea Cimarelli
Journal:  J Virol       Date:  2012-12-19       Impact factor: 5.103

9.  Cytokine influence on simian immunodeficiency virus replication within primary macrophages. TNF-alpha, but not GMCSF, enhances viral replication on a per-cell basis.

Authors:  D G Walsh; C J Horvath; A Hansen-Moosa; J J MacKey; P K Sehgal; M D Daniel; R C Desrosiers; D J Ringler
Journal:  Am J Pathol       Date:  1991-10       Impact factor: 4.307

10.  Enhanced antiviral activity against foot-and-mouth disease virus by a combination of type I and II porcine interferons.

Authors:  Mauro Pires Moraes; Teresa de Los Santos; Marla Koster; Traci Turecek; He Wang; Vladimir G Andreyev; Marvin J Grubman
Journal:  J Virol       Date:  2007-04-25       Impact factor: 5.103
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