Literature DB >> 31126931

Binge alcohol consumption leading to hypokalemic rhabdomyolysis.

Manjit Mahendran1, Shubham Agarwal1, Animesh Ray1, Naval Kishore Vikram1.   

Abstract

A 43-year-old man presented with acute onset rapidly progressive weakness in all four limbs (proximal greater than distal), following an episode of binge alcohol ingestion, and was admitted for evaluation and management. There was a history of decreased urine output since 2 days with dark-coloured urine. He was found to have severe hypokalemia and renal dysfunction. Serum creatine kinase was significantly high, and further investigation revealed significantly elevated serum and urine myoglobin levels suggestive of rhabdomyolysis, which was secondary to severe hypokalemia. Following supplementation with intravenous and oral potassium and supportive care, the weakness improved significantly, and he was subsequently discharged. This case describes severe hypokalemia, resulting in rhabdomyolysis and generalised lower motor neuron weakness, in a setting of binge alcohol ingestion, which is an entity rarely described in literature. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  fluid electrolyte and acid-base disturbances; metabolic disorders; muscle disease

Mesh:

Substances:

Year:  2019        PMID: 31126931      PMCID: PMC6536223          DOI: 10.1136/bcr-2019-229307

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  10 in total

Review 1.  Drug- and toxin-induced rhabdomyolysis.

Authors:  S C Curry; D Chang; D Connor
Journal:  Ann Emerg Med       Date:  1989-10       Impact factor: 5.721

2.  Rhabdomyolysis: an evaluation of 475 hospitalized patients.

Authors:  Giorgia Melli; Vinay Chaudhry; David R Cornblath
Journal:  Medicine (Baltimore)       Date:  2005-11       Impact factor: 1.889

3.  Mechanisms of hypophosphataemia in alcoholic patients.

Authors:  M S Elisaf; K C Siamopoulos
Journal:  Int J Clin Pract       Date:  1997 Nov-Dec       Impact factor: 2.503

4.  Hypokalemic myopathy due to chronic alcoholism.

Authors:  M E Rassouli; H Ikeda; S Otsuki
Journal:  Folia Psychiatr Neurol Jpn       Date:  1976

5.  Alcohol-associated rhabdomyolysis: ethanol induction of cytochrome P450 may potentiate myotoxicity.

Authors:  J E Riggs
Journal:  Clin Neuropharmacol       Date:  1998 Nov-Dec       Impact factor: 1.592

Review 6.  Skeletal muscle disease in alcoholism.

Authors:  R G Haller; J P Knochel
Journal:  Med Clin North Am       Date:  1984-01       Impact factor: 5.456

7.  Hypokalemic rhabdomyolysis: a rare manifestation of primary aldosteronism.

Authors:  A Zavatto; A Concistrè; C Marinelli; V Zingaretti; I Umbro; F Fiacco; F Tinti; L Petramala; A P Mitterhofer; C Letizia
Journal:  Eur Rev Med Pharmacol Sci       Date:  2015-10       Impact factor: 3.507

8.  On the mechanism of rhabdomyolysis in potassium depletion.

Authors:  J P Knochel; E M Schlein
Journal:  J Clin Invest       Date:  1972-07       Impact factor: 14.808

Review 9.  Bench-to-bedside review: Rhabdomyolysis -- an overview for clinicians.

Authors:  Ana L Huerta-Alardín; Joseph Varon; Paul E Marik
Journal:  Crit Care       Date:  2004-10-20       Impact factor: 9.097

10.  Nontraumatic rhabdomyolysis with short-term alcohol intoxication - a case report.

Authors:  Stamatis S Papadatos; Georgios Deligiannis; George Bazoukis; Paschalia Michelongona; Aikaterini Spiliopoulou; Stefanos Mylonas; Christos Zissis
Journal:  Clin Case Rep       Date:  2015-08-20
  10 in total
  1 in total

1.  Celiac Disease Complicated by Rhabdomyolysis.

Authors:  Mia Fujisawa; Masashi Matsushima; Takashi Ueda; Motoki Kaneko; Ryutaro Fujimoto; Masaya Sano; Erika Teramura; Makiko Monma; Hajime Mizukami; Fumio Nakahara; Hidekazu Suzuki; Takayoshi Suzuki
Journal:  Intern Med       Date:  2020-09-12       Impact factor: 1.271

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.