Literature DB >> 31114462

Peri-Operative Outcomes after Open and Robot-Assisted Radical Cystectomy by Using an Advanced Bipolar Seal and Cut Technology (Caiman®): A Prospective, Comparative, and Multi-Institutional Study.

Marco Borghesi1, Riccardo Schiavina1, Alessandro Antonelli2, Carlo Buizza3, Antonio Celia4, Paolo Parma5, Bernardino De Concilio4, Francesco Mengoni1, Daniele Romagnoli1, Giacomo Saraceni1, Eugenio Brunocilla1, Angelo Porreca6.   

Abstract

OBJECTIVE: To report and compare the peri-operative outcomes of patients undergoing open (ORC) and robotic-assisted radical cystectomy (RARC) for bladder cancer performed with a radiofrequency seal and cut device (Caiman®).
MATERIALS AND METHODS: Data of patients undergoing ORC or RARC between January 2015 and March 2016 at 6 Italian institutions were prospectively recorded and analyzed. Thirty-and 90-day complications were stratified according to the Martin's criteria and graded according to the Clavien-Dindo classification. Data on operative time, blood loss, transfusion rate, complications, and length of stay were evaluated and compared between the ORC and RARC groups.
RESULTS: Thirty-three (66%) and 17 (34%) patients were treated with ORC and RARC, respectively. The median age was 72 (64-78) years. Overall operative time was longer in RARC compared to ORC (389 ± 80.1 vs. 242 ± 62.2 min, p < 0.001), while the estimated blood loss during cystectomy was higher after ORC (370 ± 126.8 vs. 243.3 ± 201.6 ml, p = 0.03). The transfusion rate was significantly higher in the ORC compared to RARC (24.2 vs. 5.9%, p = 0.04). Eight (19%) and 7 (16.7%) patients experienced 30- and 90-day post-operative complications, with no significant difference between ORC and RARC. Length of stay was significantly shorter in RARC group (median 7 vs. 14 days, p < 0.001).
CONCLUSION: Open and robot-assisted procedures were safely performed by using a new advanced bipolar seal and cut technology (Caiman®). RARC demonstrated to be superior to ORC in terms of bleeding, transfusion rates and length of hospital stay, despite longer operative time.

Entities:  

Keywords:  Bladder cancer; Open radical cystectomy; Robot-assisted radical cystectomy; Sealing device

Year:  2019        PMID: 31114462      PMCID: PMC6504802          DOI: 10.1159/000489421

Source DB:  PubMed          Journal:  Curr Urol        ISSN: 1661-7649


  20 in total

1.  Perioperative outcomes and oncologic efficacy from a pilot prospective randomized clinical trial of open versus robotic assisted radical cystectomy.

Authors:  Dipen J Parekh; Jamie Messer; John Fitzgerald; Barbara Ercole; Robert Svatek
Journal:  J Urol       Date:  2012-09-24       Impact factor: 7.450

Review 2.  Systematic review and cumulative analysis of perioperative outcomes and complications after robot-assisted radical cystectomy.

Authors:  Giacomo Novara; James W F Catto; Timothy Wilson; Magnus Annerstedt; Kevin Chan; Declan G Murphy; Alexander Motttrie; James O Peabody; Eila C Skinner; Peter N Wiklund; Khurshid A Guru; Bertram Yuh
Journal:  Eur Urol       Date:  2015-01-02       Impact factor: 20.096

3.  Perioperative complications and mortality after radical cystectomy when using a standardized reporting methodology.

Authors:  Riccardo Schiavina; Marco Borghesi; Mascia Guidi; Valerio Vagnoni; Ziv Zukerman; Cristian Pultrone; Giovanni Passaretti; Daniele Romagnoli; Lorenzo Bianchi; Antonio Morselli-Labate; Eugenio Brunocilla; Marco Garofalo; Fabio Manferrari; Sergio Concetti; Giuseppe Martorana
Journal:  Clin Genitourin Cancer       Date:  2013-01-16       Impact factor: 2.872

Review 4.  Quality of complication reporting in the surgical literature.

Authors:  Robert C G Martin; Murray F Brennan; David P Jaques
Journal:  Ann Surg       Date:  2002-06       Impact factor: 12.969

5.  Comparing Open Radical Cystectomy and Robot-assisted Laparoscopic Radical Cystectomy: A Randomized Clinical Trial.

Authors:  Bernard H Bochner; Guido Dalbagni; Daniel D Sjoberg; Jonathan Silberstein; Gal E Keren Paz; S Machele Donat; Jonathan A Coleman; Sheila Mathew; Andrew Vickers; Geoffrey C Schnorr; Michael A Feuerstein; Bruce Rapkin; Raul O Parra; Harry W Herr; Vincent P Laudone
Journal:  Eur Urol       Date:  2014-12-08       Impact factor: 20.096

6.  Perioperative and oncologic outcomes of robot-assisted vs. open radical cystectomy in bladder cancer patients: A comparison of two high-volume referral centers.

Authors:  G Gandaglia; A Karl; G Novara; R de Groote; A Buchner; F D'Hondt; F Montorsi; C Stief; A Mottrie; C Gratzke
Journal:  Eur J Surg Oncol       Date:  2016-03-19       Impact factor: 4.424

7.  EAU guidelines on muscle-invasive and metastatic bladder cancer: summary of the 2013 guidelines.

Authors:  J Alfred Witjes; Eva Compérat; Nigel C Cowan; Maria De Santis; Georgios Gakis; Thierry Lebret; Maria J Ribal; Antoine G Van der Heijden; Amir Sherif
Journal:  Eur Urol       Date:  2013-12-12       Impact factor: 20.096

8.  A Single-centre Early Phase Randomised Controlled Three-arm Trial of Open, Robotic, and Laparoscopic Radical Cystectomy (CORAL).

Authors:  Muhammad Shamim Khan; Christine Gan; Kamran Ahmed; Ahmad Fahim Ismail; Jane Watkins; Jennifer A Summers; Janet L Peacock; Peter Rimington; Prokar Dasgupta
Journal:  Eur Urol       Date:  2015-08-10       Impact factor: 20.096

Review 9.  Robotic versus open radical cystectomy: an updated systematic review and meta-analysis.

Authors:  Leilei Xia; Xianjin Wang; Tianyuan Xu; Xiaohua Zhang; Zhaowei Zhu; Liang Qin; Xiang Zhang; Chen Fang; Minguang Zhang; Shan Zhong; Zhoujun Shen
Journal:  PLoS One       Date:  2015-03-31       Impact factor: 3.240

10.  Systematic review and meta-analysis of randomised trials of perioperative outcomes comparing robot-assisted versus open radical cystectomy.

Authors:  Zhiyuan Shen; Zhongquan Sun
Journal:  BMC Urol       Date:  2016-09-23       Impact factor: 2.264

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  2 in total

Review 1.  Bladder Cancer at the time of COVID-19 Outbreak.

Authors:  Francesco Esperto; Karl H Pang; Simone Albisinni; Rocco Papalia; Roberto M Scarpa
Journal:  Int Braz J Urol       Date:  2020-07       Impact factor: 1.541

2.  Bayesian network analysis of open, laparoscopic, and robot-assisted radical cystectomy for bladder cancer.

Authors:  Lin Dong; Yu Qin; Lu Ya; Cao Liang; Hu Tinghui; He Pinlin; Yang Jin; Wang Youliang; Cui Shu; Wu Tao
Journal:  Medicine (Baltimore)       Date:  2020-12-24       Impact factor: 1.817

  2 in total

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