| Literature DB >> 31112196 |
Weijian Xue1, Peter Y Zavalij, Lyle Isaacs.
Abstract
We report the synthesis of three new triazole functionalized acyclic CB[n]-type receptors (2-4) by click chemistry. The compounds have good solubility in water (≥8 mM) and do not undergo strong self-association (Ks ≤ 903 M-1). We measured the binding constants of 2-4 toward guests 9-24 and compared the results to those obtained for the prototypical acyclic CB[n]-type receptor 1. The X-ray crystal structure of 4 is also described.Entities:
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Year: 2019 PMID: 31112196 PMCID: PMC6572757 DOI: 10.1039/c9ob00906j
Source DB: PubMed Journal: Org Biomol Chem ISSN: 1477-0520 Impact factor: 3.876