Literature DB >> 31105799

Translating Mechanobiology to the Clinic: a panel discussion from the 2018 CMBE Conference.

Alisa Morss Clyne1, Michele Marcolongo1, Eric M Darling2, Nadeen O Chahine3.   

Abstract

The 2018 BMES Cellular and Molecular Bioengineering (CMBE) Conference was organized around the theme of Discovering the Keys: Transformative and Translational Mechanobiology. The conference programing included a panel discussion on Translating Mechanobiology to the Clinic. The goal of the panel was to initiate a dialog and share pearls of wisdom from participants' successes and failures in academia and in industry toward translating scientific discoveries in the field of mechanobiology to technology products in the market or toward devices or drugs that impact clinical care. This commentary reviews the major themes and questions discussed during the panel, including defining translational research and how it applies to mechanobiology, the current landscape in translational mechanobiology, the process for translating mechanobiology research, challenges in translating mechanobiology research, and unique opportunities in translating mechanobiology research.

Entities:  

Year:  2018        PMID: 31105799      PMCID: PMC6516757          DOI: 10.1007/s12195-018-0556-5

Source DB:  PubMed          Journal:  Cell Mol Bioeng        ISSN: 1865-5025            Impact factor:   2.321


  5 in total

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Authors:  J S Pober; C S Neuhauser; J M Pober
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Authors:  Shu Chien; Rashid Bashir; Robert M Nerem; Roderic Pettigrew
Journal:  Sci Transl Med       Date:  2015-04-01       Impact factor: 17.956

3.  Substrate stiffness influences the outcome of antitumor drug screening in vitro.

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4.  Regenerative rehabilitation: a new future?

Authors:  Carmen Perez-Terzic; Martin K Childers
Journal:  Am J Phys Med Rehabil       Date:  2014-11       Impact factor: 2.159

5.  Translating translation.

Authors:  Christopher P Austin
Journal:  Nat Rev Drug Discov       Date:  2018-04-20       Impact factor: 84.694

  5 in total

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