Literature DB >> 31100606

The first prototype of spot-scanning proton arc treatment delivery.

Xiaoqiang Li1, Gang Liu2, Guillaume Janssens3, Olivier De Wilde3, Vincent Bossier3, Xavier Lerot3, Antoine Pouppez3, Di Yan4, Craig Stevens4, Peyman Kabolizadeh4, Xuanfeng Ding5.   

Abstract

PURPOSE: We report the first prototype of spot-scanning arc treatment (SPArc) delivery on a clinical proton beam therapy machine and evaluate its delivery accuracy and efficiency. METHODS AND MATERIALS: A new module called Proton Dynamic Arc Delivery (PDAD) was developed to allow simultaneously delivering spot-scanning proton beam treatments while rotating the gantry on an IBA Proteus®One proton machine. A series of measurements was performed to validate the basic beam characteristics. Subsequently, patient specific quality assurance (QA) of a brain SPArc plan was performed. Total SPArc treatment delivery time was also recorded and compared to the clinically delivered intensity modulated proton therapy (IMPT) treatment time. Finally, the log file of the SPArc plan was analyzed and processed to reconstruct the actual delivered dose.
RESULTS: All the basic beam characteristics were confirmed in the PDAD mode, similar as those measured using fixed gantry deliveries in clinical mode. The brain SPArc plan with similar or superior plan quality was delivered in 4 mins compared to total 11 mins for the clinical treatment of the three-field IMPT plan. The patient QA result showed a good agreement between the measured and calculated dose distributions with the gamma index of 98.6% (3%/3 mm). The analysis of the log file confirmed the accuracy of the SPArc plan delivery, with the gamma index of 98.3% (1%/1 mm) between reconstructed and the planned doses.
CONCLUSION: The first prototype of dynamic proton arc delivery on a clinical proton therapy system was successfully performed. The measurements and simulations demonstrated the feasibility of SPArc treatment within the clinical requirements.
Copyright © 2019 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Proton arc therapy; Quality assurance; Spot scanning

Mesh:

Year:  2019        PMID: 31100606     DOI: 10.1016/j.radonc.2019.04.032

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN: 0167-8140            Impact factor:   6.280


  12 in total

1.  Fraction-variant beam orientation optimization for intensity-modulated proton therapy.

Authors:  Wenbo Gu; Daniel O'Connor; Dan Ruan; Wei Zou; Lei Dong; Ke Sheng
Journal:  Med Phys       Date:  2020-08-02       Impact factor: 4.071

2.  The accuracy of helium ion CT based particle therapy range prediction: an experimental study comparing different particle and x-ray CT modalities.

Authors:  L Volz; C-A Collins-Fekete; E Bär; S Brons; C Graeff; R P Johnson; A Runz; C Sarosiek; R W Schulte; J Seco
Journal:  Phys Med Biol       Date:  2021-11-29       Impact factor: 3.609

3.  Energy layer optimization via energy matrix regularization for proton spot-scanning arc therapy.

Authors:  Gezhi Zhang; Haozheng Shen; Yuting Lin; Ronald C Chen; Yong Long; Hao Gao
Journal:  Med Phys       Date:  2022-07-25       Impact factor: 4.506

4.  A novel energy layer optimization framework for spot-scanning proton arc therapy.

Authors:  Wenbo Gu; Dan Ruan; Qihui Lyu; Wei Zou; Lei Dong; Ke Sheng
Journal:  Med Phys       Date:  2020-03-13       Impact factor: 4.071

5.  Phase I dose-escalation trial of S-1 combined with carbon-ion radiotherapy for sinonasal squamous cell carcinoma.

Authors:  Daiki Takahashi; Yusuke Demizu; Sung Chul Park; Yoshiro Matsuo; Nor Shazrina Sulaiman; Kazuki Terashima; Sunao Tokumaru; Masaya Akashi; Tomoaki Okimoto
Journal:  J Radiat Res       Date:  2020-09-08       Impact factor: 2.724

6.  Spot-Scanning Hadron Arc (SHArc) Therapy: A Study With Light and Heavy Ions.

Authors:  Stewart Mein; Thomas Tessonnier; Benedikt Kopp; Semi Harrabi; Amir Abdollahi; Jürgen Debus; Thomas Haberer; Andrea Mairani
Journal:  Adv Radiat Oncol       Date:  2021-02-04

Review 7.  Biological and Mechanical Synergies to Deal With Proton Therapy Pitfalls: Minibeams, FLASH, Arcs, and Gantryless Rooms.

Authors:  Alejandro Mazal; Juan Antonio Vera Sanchez; Daniel Sanchez-Parcerisa; Jose Manuel Udias; Samuel España; Victor Sanchez-Tembleque; Luis Mario Fraile; Paloma Bragado; Alvaro Gutierrez-Uzquiza; Nuria Gordillo; Gaston Garcia; Juan Castro Novais; Juan Maria Perez Moreno; Lina Mayorga Ortiz; Amaia Ilundain Idoate; Marta Cremades Sendino; Carme Ares; Raymond Miralbell; Niek Schreuder
Journal:  Front Oncol       Date:  2021-01-21       Impact factor: 6.244

8.  Proton Minibeam Radiation Therapy and Arc Therapy: Proof of Concept of a Winning Alliance.

Authors:  Ramon Ortiz; Ludovic De Marzi; Yolanda Prezado
Journal:  Cancers (Basel)       Date:  2021-12-27       Impact factor: 6.639

Review 9.  Roadmap: proton therapy physics and biology.

Authors:  Harald Paganetti; Chris Beltran; Stefan Both; Lei Dong; Jacob Flanz; Keith Furutani; Clemens Grassberger; David R Grosshans; Antje-Christin Knopf; Johannes A Langendijk; Hakan Nystrom; Katia Parodi; Bas W Raaymakers; Christian Richter; Gabriel O Sawakuchi; Marco Schippers; Simona F Shaitelman; B K Kevin Teo; Jan Unkelbach; Patrick Wohlfahrt; Tony Lomax
Journal:  Phys Med Biol       Date:  2021-02-26       Impact factor: 4.174

10.  Linear Energy Transfer Incorporated Spot-Scanning Proton Arc Therapy Optimization: A Feasibility Study.

Authors:  Xiaoqiang Li; Xuanfeng Ding; Weili Zheng; Gang Liu; Guillaume Janssens; Kevin Souris; Ana M Barragán-Montero; Di Yan; Craig Stevens; Peyman Kabolizadeh
Journal:  Front Oncol       Date:  2021-07-12       Impact factor: 6.244

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