Literature DB >> 31093465

Apnea Threshold in Pediatric Brain Death: A Case with Variable Results Across Serial Examinations.

Tina Sosa1, Zachary Berrens2, Susan Conway2, Erika L Stalets2.   

Abstract

Consensus guidelines currently exist for the evaluation of pediatric patients with suspected brain death. The guidelines include the requirement for two consistent examinations separated by an observation period and a threshold of 60 mm Hg for PaCO 2 during apnea testing. We present a patient who met all prerequisites to perform brain death examination but had variability in examinations during apnea testing. We discuss our strategy in managing these unexpected findings, including the importance of open and ongoing communication with the family, and the implications for current guidelines for the determination of brain death in pediatric patients.

Entities:  

Keywords:  Pediatric; apnea; brain death

Year:  2018        PMID: 31093465      PMCID: PMC6517055          DOI: 10.1055/s-0038-1675193

Source DB:  PubMed          Journal:  J Pediatr Intensive Care        ISSN: 2146-4626


  29 in total

1.  Brain death: time for an international consensus.

Authors:  M Smith
Journal:  Br J Anaesth       Date:  2012-01       Impact factor: 9.166

2.  Brain death in children: why does it have to be so complicated?

Authors:  Eelco F M Wijdicks; Wade S Smith
Journal:  Ann Neurol       Date:  2012-04       Impact factor: 10.422

Review 3.  The apnea test: rationale, confounders, and criticism.

Authors:  Ari R Joffe; Natalie R Anton; Jonathan P Duff
Journal:  J Child Neurol       Date:  2010-05-10       Impact factor: 1.987

4.  Evidence-based guideline update: determining brain death in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology.

Authors:  Eelco F M Wijdicks; Panayiotis N Varelas; Gary S Gronseth; David M Greer
Journal:  Neurology       Date:  2010-06-08       Impact factor: 9.910

Review 5.  Implications of ischemic penumbra for the diagnosis of brain death.

Authors:  C G Coimbra
Journal:  Braz J Med Biol Res       Date:  1999-12       Impact factor: 2.590

6.  Brain death worldwide: accepted fact but no global consensus in diagnostic criteria.

Authors:  Eelco F M Wijdicks
Journal:  Neurology       Date:  2002-01-08       Impact factor: 9.910

7.  Guidelines for the determination of brain death in infants and children: an update of the 1987 Task Force recommendations.

Authors:  Thomas A Nakagawa; Stephen Ashwal; Mudit Mathur; Mohan R Mysore; Derek Bruce; Edward E Conway; Susan E Duthie; Shannon Hamrick; Rick Harrison; Andrea M Kline; Daniel J Lebovitz; Maureen A Madden; Vicki L Montgomery; Jeffrey M Perlman; Nancy Rollins; Sam D Shemie; Amit Vohra; Jacqueline A Williams-Phillips
Journal:  Crit Care Med       Date:  2011-09       Impact factor: 7.598

Review 8.  The case against confirmatory tests for determining brain death in adults.

Authors:  Eelco F M Wijdicks
Journal:  Neurology       Date:  2010-07-06       Impact factor: 9.910

9.  Variability in pediatric brain death determination and documentation in southern California.

Authors:  Mudit Mathur; LuCyndi Petersen; Maria Stadtler; Colleen Rose; J Chiaka Ejike; Floyd Petersen; Cynthia Tinsley; Stephen Ashwal
Journal:  Pediatrics       Date:  2008-05       Impact factor: 7.124

10.  A 10-month-old infant with reversible findings of brain death.

Authors:  Ari R Joffe; Hanna Kolski; Jonathan Duff; Allan R deCaen
Journal:  Pediatr Neurol       Date:  2009-11       Impact factor: 3.372

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