Literature DB >> 31088580

Use of whole-genome sequencing to guide a Clostridioides difficile diagnostic stewardship program.

Kunal K Jakharia1, Ghassan Ilaiwy1, Siobhan S Moose2, Masashi Waga3, Lakshmi Appalla4, Joel D McAlduff5, Lynne V Karanfil6, Patrick T McGann4, Glenn W Wortmann2.   

Abstract

Whole-genome sequencing (WGS) has yielded new insights into the transmission patterns of healthcare facility-onset Clostridioides difficile infection (HO-CDI). WGS results prompted a focused diagnostic stewardship program, which was associated with a significant and sustained decrease in HO-CDI at large, urban hospital.

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Year:  2019        PMID： 31088580     DOI： 10.1017/ice.2019.124

Source DB:  PubMed          Journal:  Infect Control Hosp Epidemiol        ISSN： 0899-823X            Impact factor:   3.254


  2 in total

1.  Whole-Genome Sequencing Surveillance and Machine Learning of the Electronic Health Record for Enhanced Healthcare Outbreak Detection.

Authors:  Alexander J Sundermann; Jieshi Chen; Praveen Kumar; Ashley M Ayres; Shu Ting Cho; Chinelo Ezeonwuka; Marissa P Griffith; James K Miller; Mustapha M Mustapha; A William Pasculle; Melissa I Saul; Kathleen A Shutt; Vatsala Srinivasa; Kady Waggle; Daniel J Snyder; Vaughn S Cooper; Daria Van Tyne; Graham M Snyder; Jane W Marsh; Artur Dubrawski; Mark S Roberts; Lee H Harrison
Journal:  Clin Infect Dis       Date:  2022-08-31       Impact factor: 20.999

2.  The Role of Diagnostic Stewardship in Clostridioides difficile Testing: Challenges and Opportunities.

Authors:  Frances J Boly; Kimberly A Reske; Jennie H Kwon
Journal:  Curr Infect Dis Rep       Date:  2020-02-17       Impact factor: 3.725
  2 in total

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