Literature DB >> 3107566

Production of 5-formyluracil from thymine in an in vitro active oxygen-generating system.

A Wakizaka, N Aiba, E Okuhara, Y Kawazoe.   

Abstract

Thymine was placed in a model active oxygen-generating system containing ferrous sulfate, EDTA, and ascorbic acid. The oxidative products of thymine were separated by Sephadex LH-20 chromatography and a reversed phase high-performance liquid chromatography (HPLC) into at least five major components. One of them had a UV spectrum characteristic of 5-formyluracil and mass spectrometric analysis of this material also indicated this material to be 5-formyluracil.

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Year:  1987        PMID： 3107566

Source DB:  PubMed          Journal:  Biochem Int        ISSN： 0158-5231


  4 in total

1.  Replication of DNA templates containing 5-formyluracil, a major oxidative lesion of thymine in DNA.

Authors:  Q M Zhang; H Sugiyama; I Miyabe; S Matsuda; I Saito; S Yonei
Journal:  Nucleic Acids Res       Date:  1997-10-15       Impact factor: 16.971

2.  Synthesis and properties of oligonucleotides containing 5-formyl-2'-deoxycytidine: in vitro DNA polymerase reactions on DNA templates containing 5-formyl-2'-deoxycytidine.

Authors:  N Karino; Y Ueno; A Matsuda
Journal:  Nucleic Acids Res       Date:  2001-06-15       Impact factor: 16.971

3.  The Impact of Progression on Healthcare Resource Utilization and Costs Among Patients with High-Grade Non-Muscle Invasive Bladder Cancer After Bacillus Calmette-Guérin Therapy: A Retrospective SEER-Medicare Analysis.

Authors:  Min Yang; Mihaela V Georgieva; Iryna Bocharova; Mohini Vembusubramanian; Kun Qian; Amy Guo; Ashish M Kamat
Journal:  Adv Ther       Date:  2021-01-11       Impact factor: 3.845

Review 4.  Mutagenic potentials of damaged nucleic acids produced by reactive oxygen/nitrogen species: approaches using synthetic oligonucleotides and nucleotides: survey and summary.

Authors:  Hiroyuki Kamiya
Journal:  Nucleic Acids Res       Date:  2003-01-15       Impact factor: 16.971
  4 in total

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