Penny Wright1, Sarah Wilding2, Eila Watson3, Amy Downing2, Peter Selby4, Luke Hounsome5, Richard Wagland6, David H Brewster7, Dyfed Huws8, Hugh Butcher4, Rebecca Mottram2, Therese Kearney9, Majorie Allen10, Anna Gavin9, Adam Glaser11. 1. Leeds Institute of Medical Research at St James's, University of Leeds, UK. Electronic address: e.p.wright@leeds.ac.uk. 2. Leeds Institute of Medical Research at St James's, University of Leeds, UK; Leeds Institute of Data Analytics, University of Leeds, UK. 3. Faculty of Health and Life Sciences, Oxford Brookes University, UK. 4. Leeds Institute of Medical Research at St James's, University of Leeds, UK. 5. National Cancer Registration and Analysis Service, Public Health England, UK. 6. Faculty of Health Sciences, University of Southampton, UK. 7. Deanery of Molecular, Genetic and Population Health Sciences, University of Edinburgh, UK. 8. Welsh Cancer Intelligence and Surveillance Unit, Public Health Wales, UK. 9. Northern Ireland Cancer Registry, Queen's University Belfast, Royal Victoria Hospital, Belfast, UK. 10. Leeds Teaching Hospitals NHS Trust, UK. 11. Leeds Institute of Medical Research at St James's, University of Leeds, UK; Leeds Institute of Data Analytics, University of Leeds, UK; Leeds Teaching Hospitals NHS Trust, UK.
Abstract
BACKGROUND: More men are living following a prostate cancer (PCa) diagnosis. They may need support to maximize the quality of their survival. Physical and psychological impacts of PCa are widely documented. Less is known about social impacts. We aimed to identify key factors associated with social distress following PCa. METHODS: The Life After Prostate Cancer Diagnosis study is a UK national cross-sectional survey of men 18-42 months post diagnosis of PCa. Men (n = 58 930) were invited to participate by their diagnosing cancer centre including 82% of English NHS Trusts (n = 111) and 100% of all Health Boards in Northern Ireland (n = 5), Scotland (n = 14) and Wales (n = 6). Social distress was measured using the Social Difficulties Inventory (SDI-21), 16 item Social Distress scale with men assigned to 'socially distressed'/'not socially distressed' groups, according to published guidelines. Clinical and sociodemographic variables were collected from self-report and cancer registries. RESULTS: Response rate 60.8% (n = 35 823) of whom 97% (n = 29 351) completed the Social Distress scale (mean age = 71.2; SD = 7.88). The proportion of 'socially distressed' men was 9.4%. Multivariable logistic regression analysis revealed unemployment versus employment (odds ratio (OR): 11.58 [95% CI 9.16-14.63]) and ≥3 co-morbidities versus none (OR: 5.37 [95% CI 4.61-6.27]) as key associations. Others were Androgen Deprivation Therapy, External Beam Radiotherapy in combination with another treatment, age, prior mental health problems and living in a socio-economically deprived area. CONCLUSION: Most men following PCa are socially resilient. A simple checklist could help clinicians identify men at risk of social distress.
BACKGROUND: More men are living following a prostate cancer (PCa) diagnosis. They may need support to maximize the quality of their survival. Physical and psychological impacts of PCa are widely documented. Less is known about social impacts. We aimed to identify key factors associated with social distress following PCa. METHODS: The Life After Prostate Cancer Diagnosis study is a UK national cross-sectional survey of men 18-42 months post diagnosis of PCa. Men (n = 58 930) were invited to participate by their diagnosing cancer centre including 82% of English NHS Trusts (n = 111) and 100% of all Health Boards in Northern Ireland (n = 5), Scotland (n = 14) and Wales (n = 6). Social distress was measured using the Social Difficulties Inventory (SDI-21), 16 item Social Distress scale with men assigned to 'socially distressed'/'not socially distressed' groups, according to published guidelines. Clinical and sociodemographic variables were collected from self-report and cancer registries. RESULTS: Response rate 60.8% (n = 35 823) of whom 97% (n = 29 351) completed the Social Distress scale (mean age = 71.2; SD = 7.88). The proportion of 'socially distressed' men was 9.4%. Multivariable logistic regression analysis revealed unemployment versus employment (odds ratio (OR): 11.58 [95% CI 9.16-14.63]) and ≥3 co-morbidities versus none (OR: 5.37 [95% CI 4.61-6.27]) as key associations. Others were Androgen Deprivation Therapy, External Beam Radiotherapy in combination with another treatment, age, prior mental health problems and living in a socio-economically deprived area. CONCLUSION: Most men following PCa are socially resilient. A simple checklist could help clinicians identify men at risk of social distress.
Authors: Lauren Matheson; Jo Nayoan; Carol Rivas; Jo Brett; Penny Wright; Hugh Butcher; Paul Jordan; Anna Gavin; Adam Glaser; Malcolm Mason; Richard Wagland; Eila Watson Journal: Support Care Cancer Date: 2020-07-06 Impact factor: 3.603
Authors: Clara Breidenbach; Lena Ansmann; Nora Tabea Sibert; Simone Wesselmann; Sebastian Dieng; Ernst-Günther Carl; Günter Feick; Cindy Stoklossa; Anne Taubert; Amanda Pomery; Burkhard Beyer; Andreas Blana; Marko Brock; Florian Distler; Michael Enge; Amr A Gaber; Christian Gilfrich; Andreas Hinkel; Björn Kaftan; Thomas Knoll; Frank Kunath; Simba-Joshua Oostdam; Inga Peters; Bülent Polat; Valentin Schrodi; Friedemann Zengerling; Christoph Kowalski Journal: Support Care Cancer Date: 2021-11-04 Impact factor: 3.603