| Literature DB >> 31070449 |
Tessa Reardon1, Cathy Creswell1, Kathryn J Lester2, Kristian Arendt3, Judith Blatter-Meunier4, Susan M Bögels5, Jonathan R I Coleman6, Peter J Cooper7, Einar R Heiervang8, Chantal Herren9, Sanne M Hogendoorn10, Jennifer L Hudson11, Robert Keers12, Heidi J Lyneham11, Carla E Marin13, Maaike Nauta14, Ronald M Rapee11, Susanna Roberts15, Silvia Schneider16, Wendy K Silverman13, Mikael Thastum3, Kerstin Thirlwall7, Gro Janne Wergeland17, Thalia C Eley12.
Abstract
Questionnaire measures offer a time and cost-effective alternative to full diagnostic assessments for identifying and differentiating between potential anxiety disorders and are commonly used in clinical practice. Little is known, however, about the capacity of questionnaire measures to detect specific anxiety disorders in clinically anxious preadolescent children. This study aimed to establish the ability of the Spence Children's Anxiety Scale (SCAS) subscales to identify children with specific anxiety disorders in a large clinic-referred sample (N = 1,438) of children aged 7 to 12 years. We examined the capacity of the Separation Anxiety, Social Phobia, Generalized Anxiety, and Physical Injury Fears (phobias) subscales to discriminate between children with and without the target disorder. We also identified optimal cutoff scores on subscales for accurate identification of children with the corresponding disorder, and examined the contribution of child, mother, and father reports. The Separation Anxiety subscale was able to accurately identify children with separation anxiety disorder, and this was replicated across all 3 reporters. Mother- and father-reported Social Phobia subscales also accurately identified children with social anxiety disorder, although child report was only able to accurately detect social anxiety disorder in girls. Using 2 or more reporters improved the sensitivity of the Separation Anxiety and Social Phobia subscales but reduced specificity. The Generalized Anxiety and Physical Injury Fears subscales failed to accurately identify children with the corresponding disorders. These findings have implications for the potential use of mother-, father-, and child-report SCAS subscales to detect specific disorders in preadolescent children in clinical settings. (PsycINFO Database Record (c) 2019 APA, all rights reserved).Entities:
Mesh:
Year: 2019 PMID: 31070449 PMCID: PMC6671872 DOI: 10.1037/pas0000700
Source DB: PubMed Journal: Psychol Assess ISSN: 1040-3590
Sample Characteristics
| Characteristic | |
|---|---|
| a Higher/professional = managers, directors, senior officials, professional occupations. b Other psychiatric disorders >1%. | |
| Total Sample ( | 1,438 |
| Site, | |
| Sydney, Australia | 748 (52.0) |
| Reading, UK | 400 (27.8) |
| Bergen, Norway | 111 (7.7) |
| Aarhus, Denmark | 66 (4.6) |
| Bochum, Germany | 55 (3.8) |
| Oxford, UK | 29 (2.0) |
| Miami, Florida, USA | 27 (1.9) |
| Amsterdam, the Netherlands | 2 (.1) |
| Age (years), | 9.89 (1.70) |
| Range | 7–12 |
| Gender | |
| Female, | 726 (50.5) |
| SES, | |
| Higher/professionala | 600 (41.7) |
| Other employed | 323 (22.5) |
| Unemployed | 38 (2.6) |
| Missing | 467 (32.5) |
| SCAS-C (child report; | |
| Total score | 36.11 (17.6) |
| Separation Anxiety subscale | 7.01 (4.1) |
| Social Phobia subscale | 6.04 (3.9) |
| Generalized Anxiety subscale | 7.51 (3.8) |
| Physical Injury Fears subscale | 4.47 (2.8) |
| SCAS-P (mother report; | |
| Total score | 36.47 (14.5) |
| Separation Anxiety subscale | 8.23 (4.1) |
| Social Phobia subscale | 8.21 (4.0) |
| Generalized Anxiety subscale | 7.54 (3.2) |
| Physical Injury Fears subscale | 4.67 (2.9) |
| SCAS-P (father report; | |
| Total score | 31.18 (13.2) |
| Separation Anxiety subscale | 6.92 (3.9) |
| Social Phobia subscale | 7.27 (3.8) |
| Generalized Anxiety subscale | 6.27 (2.9) |
| Physical Injury Fears subscale | 4.30 (2.7) |
| ADIS-C/P primary diagnosis, | |
| Separation anxiety disorder | 308 (21.4) |
| Social anxiety disorder | 319 (22.2) |
| Generalized anxiety disorder | 609 (42.4) |
| Panic disorder/agoraphobia | 22 (1.5) |
| Specific phobia | 164 (11.4) |
| Selective mutism | 3 (.2) |
| Anxiety disorder NOS | 13 (.9) |
| Primary diagnosis CSR, | 6.17 (1.0) |
| Presence of anxiety disorder, | |
| Separation anxiety disorder | 743 (51.7) |
| Social anxiety disorder | 913 (63.5) |
| Generalized anxiety disorder | 1,078 (75.0) |
| Panic disorder | 31(2.2) |
| Agoraphobia | 23 (1.6) |
| Specific phobia | 715 (49.7) |
| Selective mutism | 18 (1.3) |
| Anxiety disorder NOS | 18 (1.3) |
| Presence of other psychiatric disorders,b
| |
| OCD | 85 (5.9) |
| Major depressive disorder or dysthymia | 137 (9.5) |
| ADHD | 158 (11.0) |
| ODD | 152 (10.6) |
Differences in Child, Mother, and Father Reports on SCAS-C/P Subscales Among Children With and Without the Target Anxiety Disorder
| SCAS-C/P subscale | Reporter | Gender | Target disorder | No target disorder | |
|---|---|---|---|---|---|
| * | |||||
| Separation anxiety | Child | Girls | 9.28 (3.76) | 5.61 (3.55) | |
| ( | ( | ||||
| Boys | 7.94 (3.93) | 4.90 (3.46) | |||
| ( | ( | ||||
| Mother | Girls | 10.55 (3.33) | 6.17 (3.34) | ||
| ( | ( | ||||
| Boys | 10.03 (3.62) | 5.85 (3.43) | |||
| ( | ( | ||||
| Father | Girls | 9.03 (3.53) | 5.27 (3.12) | ||
| ( | ( | ||||
| Boys | 8.40 (3.84) | 5.14 (3.20) | |||
| ( | ( | ||||
| Social phobia | Child | Girls | 7.48 (3.90) | 4.71 (3.27) | |
| ( | ( | ||||
| Boys | 6.34 (3.90) | 4.36 (3.33) | |||
| ( | ( | ||||
| Mother | Girls | 9.73 (3.81) | 5.97 (3.56) | ||
| ( | ( | ||||
| Boys | 9.16 (3.74) | 6.13 (3.45) | |||
| ( | ( | ||||
| Father | Girls | 8.54 (3.73) | 5.21 (3.18) | ||
| ( | ( | ||||
| Boys | 8.19 (3.67) | 5.64 (3.27) | |||
| ( | ( | ||||
| Generalized anxiety | Child | Girls | 8.47 (3.93) | 6.93 (3.35) | |
| ( | ( | ||||
| Boys | 7.19 (3.55) | 6.16 (3.57) | |||
| ( | ( | ||||
| Mother | Girls | 8.10 (3.31) | 6.93 (3.32) | ||
| ( | ( | ||||
| Boys | 7.51 (3.17) | 6.59 (2.83) | |||
| ( | ( | ||||
| Father | Girls | 6.55 (2.89) | 5.80 (2.83) | ||
| ( | ( | ||||
| Boys | 6.33 (2.84) | 5.56 (2.76) | |||
| ( | ( | ||||
| Physical injury fears | Child | Girls | 5.46 (2.65) | 4.29 (2.82) | |
| ( | ( | ||||
| Boys | 4.45 (3.08) | 3.31 (2.48) | |||
| ( | ( | ||||
| Mother | Girls | 5.74 (2.90) | 3.99 (2.52) | ||
| ( | ( | ||||
| Boys | 5.12 (2.82) | 3.55 (2.63) | |||
| ( | ( | ||||
| Father | Girls | 5.15 (2.57) | 3.36 (2.40) | ||
| ( | ( | ||||
| Boys | 4.71 (2.72) | 3.34 (2.57) | |||
| ( | ( | ||||
Receiver Operating Characteristics (ROCs) for Child-, Mother-, and Father-Report SCAS-C/P Subscales
| SCAS-C/P subscale | ROC statistics | Girls | Boys | ||||
|---|---|---|---|---|---|---|---|
| Child | Mother | Father | Child | Mother | Father | ||
| Separation anxiety | SEP (positive), | 411 | 411 | 252 | 332 | 332 | 212 |
| No SEP (negative), | 315 | 315 | 223 | 379 | 379 | 265 | |
| AUC | .76 | .82 | .79 | .73 | .80 | .74 | |
| Optimal cut score | 6.5 | 8.5 | 6.5 | 5.5 | 7.5 | 6.5 | |
| Sensitivity | .75 | .73 | .78 | .73 | .78 | .70 | |
| Specificity | .64 | .75 | .70 | .62 | .69 | .69 | |
| Correct classification, | 507 (70.0) | 537 (74.0) | 354 (74.5) | 477 (67.1) | 521 (73.3) | 331 (69.4) | |
| Social phobia | SAD (positive), | 458 | 458 | 297 | 455 | 455 | 302 |
| No SAD (negative), | 268 | 268 | 178 | 256 | 256 | 175 | |
| AUC | .71 | .77 | .75 | .65 | .72 | .70 | |
| Optimal cut score | 5.5 | 7.5 | 6.5 | 7.5 | 6.5 | ||
| Sensitivity | .67 | .71 | .70 | .66 | .67 | ||
| Specificity | .65 | .71 | .69 | .67 | .63 | ||
| Correct classification, | 481 (66.3) | 515 (71.0) | 329 (69.3) | 470 (66.1) | 312 (65.4) | ||
| Generalized anxiety | GAD (positive), | 535 | 535 | 365 | 543 | 543 | 376 |
| No GAD (negative), | 191 | 191 | 110 | 168 | 168 | 101 | |
| AUC | .61 | .62 | .58 | .58 | .57 | .58 | |
| Optimal cut score | |||||||
| Sensitivity | |||||||
| Specificity | |||||||
| Correct classification, | |||||||
| Physical injury fears | SP (positive), | 381 | 381 | 271 | 334 | 334 | 248 |
| No SP (negative), | 292 | 292 | 181 | 320 | 320 | 201 | |
| AUC | .62 | .68 | .70 | .60 | .67 | .65 | |
| Optimal cut score | 4.5 | ||||||
| Sensitivity | .61 | ||||||
| Specificity | .71 | ||||||
| Correct classification, | 292 (64.6) | ||||||
Contribution of Child-, Mother-, and Father-Reported SCAS-C/P Subscales in Identifying Children With the Target Anxiety Disorders
| Target anxiety disorder | Girls | Boys | ||||||
|---|---|---|---|---|---|---|---|---|
| Odds ratio [95% CI] | Model | Odds ratio [95% CI] | Model | |||||
| * | ||||||||
| SEP | ||||||||
| Constant | −3.89 (103.29***) | −3.10 (97.98***) | ||||||
| Child | .13 (12.69***) | 1.14 [1.06, 1.22] | .35 (Cox & Snell) .46 (Nagelkerke) | χ2(3) = 201.15*** | .14 (18.14***) | 1.14 [1.08, 1.22] | .26 (Cox & Snell) .35 (Nagelkerke) | χ2(3) = 144.63*** |
| Mother | .24 (31.99***) | 1.27 [1.17, 1.39] | .16 (16.32***) | 1.17 [1.09, 1.27] | ||||
| Father | .14 (11.70***) | 1.15 [1.06, 1.25] | .11 (7.62**) | 1.11 [1.03, 1.20] | ||||
| SAD | ||||||||
| Constant | −2.50 (62.37***) | −1.82 (39.59***) | ||||||
| Child | .12 (12.37***) | 1.12 [1.05, 1.20] | .25 (Cox & Snell) .34 (Nagelkerke) | χ2(3) = 137.19*** | .11 (11.08***) | 1.11 [1.05, 1.18] | .18 (Cox & Snell) .24 (Nagelkerke) | χ2(3) = 93.04*** |
| Mother | .15 (16.78***) | 1.16 [1.08, 1.25] | .15 (17.56***) | 1.16 [1.08, 1.24] | ||||
| Father | .17 (18.94***) | 1.18 [1.10, 1.27] | .10 (6.89**) | 1.10 [1.03, 1.18] | ||||
| GAD | ||||||||
| Constant | .00 (00, | .21 (.38, | ||||||
| Child | .07 (3.92, | 1.07 [1.00, 1.14] | .03 (Cox & Snell) .05 (Nagelkerke) | χ2(3) = 14.54** | .04 (1.33, | 1.04 [.97, 1.12] | .02 (Cox & Snell) .04 (Nagelkerke) | χ2(3) = 11.36*** |
| Mother | .05 (1.59, | 1.05 [.97, 1.14) | .07 (2.60, | 1.08 [.99, 1.17] | ||||
| Father | .05 (1.05, | 1.05 [.96, .1.15] | .05 (1.19, | 1.05 [.96, 1.16] | ||||
| SP | ||||||||
| Constant | −1.09 (19.70***) | −.88 (17.96***) | ||||||
| Child | .01 (.10, | 1.01 [.93, 1.11] | .12 (Cox & Snell) .17 (Nagelkerke) | χ2(3) = 59.65*** | .07 (2.88, | 1.07 [.99, 1.16] | .08 (Cox & Snell) .11 (Nagelkerke) | χ2(3) = 38.97*** |
| Mother | .11 (4.84*) | 1.12 [1.01, 1.23] | .11 (4.42*) | 1.11 [1.01, 1.23] | ||||
| Father | .21 (15.32***) | 1.24 [1.11, 1.37] | .09 (2.74, | 1.09 [.98, 1.21] | ||||
Identifying Separation Anxiety Disorders and Social Anxiety Disorders Using the Corresponding SCAS-C/P Subscale With Multiple Reporters (Child, Mother, Father)
| SCAS-C/P reporter(s) | Separation anxiety disorder | Social anxiety disorder | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Girls | Boys | Girls | |||||||
| Sensitivity | Specificity | Correct classification
| Sensitivity | Specificity | Correct classification
| Sensitivity | Specificity | Correct classification
| |
| Child–mother | .88 | .52 | 528 (72.7) | .92 | .50 | 494 (69.5) | .87 | .51 | 533 (73.4) |
| Child–father | .91 | .49 | 339 (71.3) | .92 | .49 | 325 (68.1) | .87 | .46 | 341 (71.8) |
| Mother–father | .88 | .60 | 355 (74.7) | .84 | .57 | 329 (68.9) | .84 | .56 | 348 (73.2) |
| Child-mother-father | .93 | .45 | 335 (70.5) | .94 | .44 | 317 (66.5) | .92 | .40 | 343 (72.2) |