| Literature DB >> 31061159 |
Maria Karlsson1, Richard A Stanton2, Uzma Ansari2, Gillian McAllister2, Monica Y Chan2,3, Erisa Sula2,3, Julian E Grass2, Nadezhda Duffy2, Melissa L Anacker4, Medora L Witwer4, J Kamile Rasheed2, Christopher A Elkins2, Alison Laufer Halpin2,5.
Abstract
We report on a carbapenemase-producing hypervirulent Klebsiella pneumoniae (CP-hvKP) isolate collected from a U.S. patient at an outpatient clinic. The isolate was identified as K. pneumoniae serotype K1 sequence type 23 and included both a hypervirulence (with rmpA, rmpA2 iroBCDN, peg-344, and iucABCD-iutA genes) and a carbapenemase-encoding (bla KPC-2) plasmid. The emergence of CP-hvKP underscores the importance of clinical awareness of this pathotype and the need for continued monitoring of CP-hvKP in the United States. This is a work of the U.S. Government and is not subject to copyright protection in the United States. Foreign copyrights may apply.Entities:
Keywords: Klebsiellazzm321990; hypervirulence; plasmid-mediated resistance
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Year: 2019 PMID： 31061159 PMCID： PMC6591612 DOI： 10.1128/AAC.00519-19
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191