Natalie Slopen1, Garrett Strizich2, Simin Hua2, Linda C Gallo3, David H Chae4, Naomi Priest5, Matthew J Gurka6, Shrikant I Bangdiwala7, Julia I Bravin3, Earle C Chambers8, Martha L Daviglus9, Maria M Llabre10, Mercedes R Carnethon11, Carmen R Isasi2. 1. Department of Epidemiology and Biostatistics, University of Maryland, College Park. Electronic address: nslopen@umd.edu. 2. Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY. 3. Department of Psychology, San Diego State University, San Diego, CA. 4. Department of Human Development and Family Studies, Auburn University, Auburn, AL. 5. ANU Centre for Social Research and Methods, College of Arts and Social Sciences, Australian National University, Canberra, Australia; Population Health, Murdoch Children's Research Institute, Melbourne, Australia. 6. Department of Health Outcomes & Biomedical Informatics, University of Florida, Gainesville. 7. Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada. 8. Department of Family and Social Medicine, Bronx, NY. 9. Institute for Minority Health Research, College of Medicine, University of Illinois, Chicago. 10. Department of Psychology, University of Miami, Coral Gables, FL. 11. Department of Preventive Medicine, Northwestern University, Chicago, IL.
Abstract
PURPOSE: Limited research has examined maternal experiences of racial/ethnic discrimination in relation to child cardiometabolic health. In this study, we investigated whether maternal experiences of ethnic discrimination were associated with cardiometabolic risk in Hispanic/Latino youth several years later. METHODS: Our sample included 1146 youth (8-16 years) from the Study of Latino Youth (2012-2014), who were children of the Hispanic Community Health Study/Study of Latinos participants (2008-2011). We used regression models to examine the prospective associations between maternal report of ethnic discrimination in relation to her child's body mass index (BMI) z-score, metabolic syndrome score (MetS), and high sensitivity C-reactive protein (hsCRP) levels 2 years later. RESULTS: Maternal ethnic discrimination was associated with youth hsCRP, but not BMI or MetS (P-values >.05). Adjusting for age, nativity, and national background, maternal ethnic discrimination was associated with higher (log) hsCRP levels (β = 0.18, 95% CI = 0.04 to 0.32) in children. This association was robust to adjustment for maternal and household characteristics (β = 0.17, 95% CI = 0.04 to 0.31), as well as maternal depression and maternal BMI. CONCLUSIONS: Maternal ethnic discrimination is associated with inflammation among Hispanic/Latino youth, and not BMI z-score or MetS. Studies are needed to address temporality and pathways.
PURPOSE: Limited research has examined maternal experiences of racial/ethnic discrimination in relation to child cardiometabolic health. In this study, we investigated whether maternal experiences of ethnic discrimination were associated with cardiometabolic risk in Hispanic/Latino youth several years later. METHODS: Our sample included 1146 youth (8-16 years) from the Study of Latino Youth (2012-2014), who were children of the Hispanic Community Health Study/Study of Latinos participants (2008-2011). We used regression models to examine the prospective associations between maternal report of ethnic discrimination in relation to her child's body mass index (BMI) z-score, metabolic syndrome score (MetS), and high sensitivity C-reactive protein (hsCRP) levels 2 years later. RESULTS: Maternal ethnic discrimination was associated with youth hsCRP, but not BMI or MetS (P-values >.05). Adjusting for age, nativity, and national background, maternal ethnic discrimination was associated with higher (log) hsCRP levels (β = 0.18, 95% CI = 0.04 to 0.32) in children. This association was robust to adjustment for maternal and household characteristics (β = 0.17, 95% CI = 0.04 to 0.31), as well as maternal depression and maternal BMI. CONCLUSIONS: Maternal ethnic discrimination is associated with inflammation among Hispanic/Latino youth, and not BMI z-score or MetS. Studies are needed to address temporality and pathways.
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