Literature DB >> 3106080

Cross-reactive monoclonal antibodies to alcohol dehydrogenases.

B G Talbot, G Bilodeau.   

Abstract

Three anti-horse liver alcohol dehydrogenase (HLADH) monoclonal antibodies are described. Two are specific for ADH and cross-react with class I and II enzymes from mouse, horse and Chinese hamster. They are specific for the native enzyme but do not inhibit enzyme activity except when combined at high concentration. The third antibody was isolated as a response to rabbit metallothionein. It binds metalloproteins and inhibits ADH activity.

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Year:  1987        PMID: 3106080     DOI: 10.1007/bf01940438

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  10 in total

1.  Monoclonal antibodies against metallothioneins and metalloproteins.

Authors:  B G Talbot; G Bilodeau; J P Thirion
Journal:  Mol Immunol       Date:  1986-10       Impact factor: 4.407

2.  Monoclonal hybridoma screening by analysis of immunoglobulin light chains.

Authors:  B G Talbot; S J MacLean; D M Gibson
Journal:  J Immunol Methods       Date:  1985-05-23       Impact factor: 2.303

3.  Heterogeneity and new molecular forms of human liver alcohol dehydrogenase.

Authors:  W F Bosron; T K Li; B L Vallee
Journal:  Biochem Biophys Res Commun       Date:  1979-12-28       Impact factor: 3.575

4.  Isozymes of human liver alcohol dehydrogenase.

Authors:  B L Vallee; T J Bazzone
Journal:  Isozymes Curr Top Biol Med Res       Date:  1983

5.  Purification and properties of two distinct groups of ADH isozymes from Chinese hamster liver.

Authors:  B G Talbot; A A Qureshi; R Cohen; J P Thirion
Journal:  Biochem Genet       Date:  1981-08       Impact factor: 1.890

6.  Characterization of human alcohol dehydrogenase isoenzymes by high-performance liquid chromatographic peptide mapping.

Authors:  D J Strydom; B L Vallee
Journal:  Anal Biochem       Date:  1982-07-01       Impact factor: 3.365

7.  Inhibitory monoclonal antibodies against rat liver alcohol dehydrogenase.

Authors:  P J Lad; D B Schenk; H L Leffert
Journal:  Arch Biochem Biophys       Date:  1984-12       Impact factor: 4.013

8.  Immunological and biochemical characterization of the human alcohol dehydrogenase chi-ADH isozyme.

Authors:  A Adinolfi; M Adinolfi; D A Hopkinson
Journal:  Ann Hum Genet       Date:  1984-01       Impact factor: 1.670

9.  Alcohol dehydrogenase mutants of Chinese hamster somatic cells resistant to allyl alcohol.

Authors:  J P Thirion; B Talbot
Journal:  Genetics       Date:  1978-02       Impact factor: 4.562

10.  chi-ADH is the sole alcohol dehydrogenase isozyme of mammalian brains: implications and inferences.

Authors:  T B Beisswenger; B Holmquist; B L Vallee
Journal:  Proc Natl Acad Sci U S A       Date:  1985-12       Impact factor: 11.205

  10 in total

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