Claudia K Fox1, Amy C Gross2, Eric M Bomberg2, Justin R Ryder2, Megan M Oberle2, Carolyn T Bramante2, Aaron S Kelly2. 1. Center for Pediatric Obesity Medicine, Department of Pediatrics, University of Minnesota, 2450 Riverside Avenue, 6th floor, East Bldg, Minneapolis, MN, 55454, USA. Lusc0001@umn.edu. 2. Center for Pediatric Obesity Medicine, Department of Pediatrics, University of Minnesota, 2450 Riverside Avenue, 6th floor, East Bldg, Minneapolis, MN, 55454, USA.
Abstract
PURPOSE OF REVIEW: This review describes (1) the clinical assessment of pediatric patients with severe obesity, including a summary of salient biological, psychological, and social factors that may be contributing to the patient's obesity and (2) the current state of treatment strategies for pediatric severe obesity, including lifestyle modification therapy, pharmacotherapy, and metabolic and bariatric surgery. RECENT FINDINGS: Lifestyle modification therapy alone is insufficient for achieving clinically significant BMI reduction for most youth with severe obesity and metabolic and bariatric surgery, though effective and durable, is not a scalable treatment strategy. Pharmacological agents in the pipeline may 1 day fill this gap in treatment. Treatment of severe pediatric obesity requires a chronic care management approach utilizing multidisciplinary teams of health care providers and multi-pronged therapies.
PURPOSE OF REVIEW: This review describes (1) the clinical assessment of pediatric patients with severe obesity, including a summary of salient biological, psychological, and social factors that may be contributing to the patient's obesity and (2) the current state of treatment strategies for pediatric severe obesity, including lifestyle modification therapy, pharmacotherapy, and metabolic and bariatric surgery. RECENT FINDINGS: Lifestyle modification therapy alone is insufficient for achieving clinically significant BMI reduction for most youth with severe obesity and metabolic and bariatric surgery, though effective and durable, is not a scalable treatment strategy. Pharmacological agents in the pipeline may 1 day fill this gap in treatment. Treatment of severe pediatric obesity requires a chronic care management approach utilizing multidisciplinary teams of health care providers and multi-pronged therapies.
Entities:
Keywords:
Adolescent; Assessment and treatment; Bariatric surgery; Child; Obesity; Pediatric; Pharmacotherapy; Severe obesity; Weight loss surgery
Authors: Michael L Dansinger; Joi Augustin Gleason; John L Griffith; Harry P Selker; Ernst J Schaefer Journal: JAMA Date: 2005-01-05 Impact factor: 56.272
Authors: James R Bailes; Misty T Strow; Joseph Werthammer; Richard A McGinnis; Yoram Elitsur Journal: Metab Syndr Relat Disord Date: 2003-09 Impact factor: 1.894
Authors: Philip R Schauer; Bartolome Burguera; Sayeed Ikramuddin; Dan Cottam; William Gourash; Giselle Hamad; George M Eid; Samer Mattar; Ramesh Ramanathan; Emma Barinas-Mitchel; R Harsha Rao; Lewis Kuller; David Kelley Journal: Ann Surg Date: 2003-10 Impact factor: 12.969
Authors: Christine B San Giovanni; Brooke Sweeney; Joseph A Skelton; Megan M Kelsey; Aaron S Kelly Journal: J Clin Endocrinol Metab Date: 2021-06-16 Impact factor: 5.958
Authors: Vidhu V Thaker; Stavroula K Osganian; Sarah D deFerranti; Kendrin R Sonneville; Jennifer K Cheng; Henry A Feldman; Tracy K Richmond Journal: BMC Pediatr Date: 2020-06-10 Impact factor: 2.125
Authors: Eric M Bomberg; Elise F Palzer; Kyle D Rudser; Aaron S Kelly; Carolyn T Bramante; Hilary K Seligman; Favour Noni; Claudia K Fox Journal: Ther Adv Endocrinol Metab Date: 2022-04-11 Impact factor: 4.435