| Literature DB >> 31048766 |
Run-Wen Yao1, Yang Wang1, Ling-Ling Chen2,3.
Abstract
A diverse catalog of long noncoding RNAs (lncRNAs), which lack protein-coding potential, are transcribed from the mammalian genome. They are emerging as important regulators in gene expression networks by controlling nuclear architecture and transcription in the nucleus and by modulating mRNA stability, translation and post-translational modifications in the cytoplasm. In this Review, we highlight recent progress in cellular functions of lncRNAs at the molecular level in mammalian cells.Entities:
Mesh：
Substances：
Year: 2019 PMID： 31048766 DOI： 10.1038/s41556-019-0311-8
Source DB: PubMed Journal: Nat Cell Biol ISSN： 1465-7392 Impact factor: 28.824