Mary E Duffy1, Anna R Gai1, Megan L Rogers1, Thomas E Joiner1, Joan L Luby2, Paramjit T Joshi3, Karen D Wagner4, Graham J Emslie5,6, John T Walkup7, David Axelson8. 1. Department of Psychology, Florida State University, Tallahassee, Florida. 2. Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri. 3. Department of Psychiatry, University of California, Irvine, California. 4. Department of Psychiatry, University of Texas Medical Branch, Galveston, Texas. 5. Division of Child and Adolescent Psychiatry, Children's Medical Center, Dallas, Texas. 6. Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas. 7. Department of Psychiatry, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois. 8. Nationwide Children's Hospital Research Institute, The Ohio State University College of Medicine, Columbus, Ohio.
Abstract
OBJECTIVES: The purpose of this study was to explore associations between specific types of hallucinations and delusions and suicidal ideation in a sample of children and adolescents with bipolar I disorder. METHODS: Participants (N = 379) were children and adolescents aged 6-15 years (M = 10.2, SD = 2.7) with DSM-IV diagnoses of bipolar I disorder, mixed or manic phase. The study sample was 53.8% female and primarily White (73.6% White, 17.9% Black, and 8.5% Other). Presence and nature of psychotic symptoms, suicidal ideation, and functioning level were assessed through clinician-administered measures. A series of logistic regressions was performed to assess the contribution of each subtype of psychotic symptom to the presence of suicidal ideation above and beyond age, sex, socio-economic status, age at bipolar disorder onset, and global level of functioning. RESULTS: Hallucinations overall, delusions of guilt, and number of different psychotic symptom types were uniquely associated with increased odds of suicidal ideation after accounting for covariates. Other forms of delusions (eg, grandiose) and specific types of hallucinations (eg, auditory) were not significantly uniquely associated with the presence of suicidal ideation. CONCLUSIONS: Findings of this study suggest the presence of hallucinations as a whole, delusions of guilt specifically, and having multiple concurrent types of psychotic symptoms are associated with the presence of suicidal ideation in children and adolescents with bipolar I disorder. Psychotic symptom subtypes, as opposed to psychosis as a whole, are an under-examined, potentially important, area for consideration regarding suicidal ideation in pediatric bipolar I disorder.
OBJECTIVES: The purpose of this study was to explore associations between specific types of hallucinations and delusions and suicidal ideation in a sample of children and adolescents with bipolar I disorder. METHODS:Participants (N = 379) were children and adolescents aged 6-15 years (M = 10.2, SD = 2.7) with DSM-IV diagnoses of bipolar I disorder, mixed or manic phase. The study sample was 53.8% female and primarily White (73.6% White, 17.9% Black, and 8.5% Other). Presence and nature of psychotic symptoms, suicidal ideation, and functioning level were assessed through clinician-administered measures. A series of logistic regressions was performed to assess the contribution of each subtype of psychotic symptom to the presence of suicidal ideation above and beyond age, sex, socio-economic status, age at bipolar disorder onset, and global level of functioning. RESULTS:Hallucinations overall, delusions of guilt, and number of different psychotic symptom types were uniquely associated with increased odds of suicidal ideation after accounting for covariates. Other forms of delusions (eg, grandiose) and specific types of hallucinations (eg, auditory) were not significantly uniquely associated with the presence of suicidal ideation. CONCLUSIONS: Findings of this study suggest the presence of hallucinations as a whole, delusions of guilt specifically, and having multiple concurrent types of psychotic symptoms are associated with the presence of suicidal ideation in children and adolescents with bipolar I disorder. Psychotic symptom subtypes, as opposed to psychosis as a whole, are an under-examined, potentially important, area for consideration regarding suicidal ideation in pediatric bipolar I disorder.
Authors: Erik B Hysinger; S Todd Callahan; T Lynne Caples; D Catherine Fuchs; Richard Shelton; William O Cooper Journal: Pediatrics Date: 2011-08-08 Impact factor: 7.124
Authors: R E Ulloa; B Birmaher; D Axelson; D E Williamson; D A Brent; N D Ryan; J Bridge; M Baugher Journal: J Am Acad Child Adolesc Psychiatry Date: 2000-03 Impact factor: 8.829
Authors: Alexandre Paim Diaz; Valeria A Cuellar; Elizabeth L Vinson; Robert Suchting; Kathryn Durkin; Brisa S Fernandes; Giselli Scaini; Iram Kazimi; Giovana B Zunta-Soares; João Quevedo; Marsal Sanches; Jair C Soares Journal: Front Psychiatry Date: 2021-06-04 Impact factor: 4.157