Literature DB >> 31020551

tRNAscan-SE: Searching for tRNA Genes in Genomic Sequences.

Patricia P Chan1, Todd M Lowe2.   

Abstract

Transfer RNAs are the largest, most complex non-coding RNA family, universal to all living organisms. tRNAscan-SE has been the de facto tool for predicting tRNA genes in whole genomes. The newly developed version 2.0 has incorporated advanced methodologies with improved probabilistic search software and a suite of new gene models, enabling better functional classification of predicted genes. This chapter describes the use of the UNIX command-driven and online web versions, illustrating different search modes and options.

Entities:  

Keywords:  Covariance model; Gene prediction; Non-coding RNA; RNA secondary structure; Transfer RNA

Mesh:

Substances:

Year:  2019        PMID: 31020551      PMCID: PMC6768409          DOI: 10.1007/978-1-4939-9173-0_1

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  315 in total

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Authors:  Yang Liu; Kira S Makarova; Wen-Cong Huang; Yuri I Wolf; Anastasia N Nikolskaya; Xinxu Zhang; Mingwei Cai; Cui-Jing Zhang; Wei Xu; Zhuhua Luo; Lei Cheng; Eugene V Koonin; Meng Li
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