| Literature DB >> 31005420 |
Sabina Sevcikova1, Jiri Minarik2, Martin Stork3, Tomas Jelinek4, Ludek Pour5, Roman Hajek6.
Abstract
Extramedullary disease of multiple myeloma (EM) remains a treatment challenge even in the era of new drugs. While many reports analyzing various aspects of EM have been published, mechanism of EM development has not been clarified yet. This review summarizes current knowledge about this clinical entity, including its history, diagnostics, imaging methods, incidence, prognosis, current treatment options, risk factors and known molecular mechanisms that might be involved in pathogenesis of EM.Entities:
Keywords: Biomarker; Extramedullary disease; Multiple myeloma; Resistance; Treatment
Mesh：
Year: 2019 PMID： 31005420 DOI： 10.1016/j.blre.2019.04.002
Source DB: PubMed Journal: Blood Rev ISSN： 0268-960X Impact factor: 8.250