Literature DB >> 30992633

Implementing prevention policies for mother-to-child transmission of HIV in rural Malawi, South Africa and United Republic of Tanzania, 2013-2016.

Harriet Jones1, Alison Wringe1, Jim Todd1, John Songo2, Francesc Xavier Gómez-Olivé3, Mosa Moshabela4, Eveline Geubbels1,2,3,4,5,6,7, Mukome Nyamhagatta5, Thoko Kalua6, Mark Urassa7, Basia Zaba1, Jenny Renju1.   

Abstract

OBJECTIVE: To assess adoption of World Health Organization (WHO) guidance into national policies for prevention of mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) and to monitor implementation of guidelines at facility level in rural Malawi, South Africa and the United Republic of Tanzania.
METHODS: We summarized national PMTCT policies and WHO guidance for 15 indicators across the cascades of maternal and infant care over 2013-2016. Two survey rounds were conducted (2013-2015 and 2015-2016) in 46 health facilities serving five health and demographic surveillance system populations. We administered structured questionnaires to facility managers to describe service delivery. We report the proportions of facilities implementing each indicator and the frequency and durations of stock-outs of supplies, by site and survey round.
FINDINGS: In all countries, national policies influencing the maternal and infant PMTCT cascade of care aligned with WHO guidelines by 2016; most inter-country policy variations concerned linkage to routine HIV care. The proportion of facilities delivering post-test counselling, same-day antiretroviral therapy (ART) initiation, antenatal care and ART provision in the same building, and Option B+ increased or remained at 100% in all sites. Progress in implementing policies on infant diagnosis and treatment varied across sites. Stock-outs of HIV test kits or antiretroviral drugs in the past year declined overall, but were reported by at least one facility per site in both rounds.
CONCLUSION: Progress has been made in implementing PMTCT policy in these settings. However, persistent gaps across the infant cascade of care and supply-chain challenges, risk undermining infant HIV elimination goals.

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Year:  2019        PMID: 30992633      PMCID: PMC6453322          DOI: 10.2471/BLT.18.217471

Source DB:  PubMed          Journal:  Bull World Health Organ        ISSN: 0042-9686            Impact factor:   9.408


  22 in total

1.  Brief Report: HIV Testing Among Pregnant Women Who Attend Antenatal Care in Malawi.

Authors:  Lyson Tenthani; Andreas D Haas; Matthias Egger; Joep J Van Oosterhout; Andreas Jahn; Frank Chimbwandira; Kali Tal; Landon Myer; Janne Estill; Olivia Keiser
Journal:  J Acquir Immune Defic Syndr       Date:  2015-08-15       Impact factor: 3.731

2.  Retention in care during the first 3 years of antiretroviral therapy for women in Malawi's option B+ programme: an observational cohort study.

Authors:  Andreas D Haas; Lyson Tenthani; Malango T Msukwa; Kali Tal; Andreas Jahn; Oliver J Gadabu; Adrian Spoerri; Frank Chimbwandira; Joep J van Oosterhout; Olivia Keiser
Journal:  Lancet HIV       Date:  2016-03-09       Impact factor: 12.767

3.  Data Resource Profile: Network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA Network).

Authors:  Georges Reniers; Marylene Wamukoya; Mark Urassa; Amek Nyaguara; Jessica Nakiyingi-Miiro; Tom Lutalo; Vicky Hosegood; Simon Gregson; Xavier Gómez-Olivé; Eveline Geubbels; Amelia C Crampin; Alison Wringe; Laban Waswa; Stephen Tollman; Jim Todd; Emma Slaymaker; David Serwadda; Alison Price; Samuel Oti; Moffat J Nyirenda; Dorean Nabukalu; Constance Nyamukapa; Fred Nalugoda; Owen Mugurungi; Baltazar Mtenga; Lisa Mills; Denna Michael; Estelle McLean; Nuala McGrath; Emmanuel Martin; Milly Marston; Sewe Maquins; Francis Levira; Catherine Kyobutungi; Daniel Kwaro; Ivan Kasamba; Chifundo Kanjala; Kathleen Kahn; Chodziwadziwa Kabudula; Kobus Herbst; Dickman Gareta; Jeffrey W Eaton; Samuel J Clark; Kathryn Church; Menard Chihana; Clara Calvert; Donatien Beguy; Gershim Asiki; Shamte Amri; Ramadhani Abdul; Basia Zaba
Journal:  Int J Epidemiol       Date:  2016-03-10       Impact factor: 7.196

4.  A comparative analysis of national HIV policies in six African countries with generalized epidemics.

Authors:  Kathryn Church; Francis Kiweewa; Aisha Dasgupta; Mary Mwangome; Edith Mpandaguta; Francesc Xavier Gómez-Olivé; Samuel Oti; Jim Todd; Alison Wringe; Eveline Geubbels; Amelia Crampin; Jessica Nakiyingi-Miiro; Chika Hayashi; Muthoni Njage; Ryan G Wagner; Alex Riolexus Ario; Simon D Makombe; Owen Mugurungi; Basia Zaba
Journal:  Bull World Health Organ       Date:  2015-04-28       Impact factor: 9.408

Review 5.  Lessons learned from early implementation of option B+: the Elizabeth Glaser Pediatric AIDS Foundation experience in 11 African countries.

Authors:  Mary Pat Kieffer; Meghan Mattingly; Anja Giphart; Roland van de Ven; Caspian Chouraya; Moses Walakira; Alexandre Boon; Silvia Mikusova; R J Simonds
Journal:  J Acquir Immune Defic Syndr       Date:  2014-12-01       Impact factor: 3.731

6.  Implementation and operational research: the impact of option B+ on the antenatal PMTCT cascade in Lilongwe, Malawi.

Authors:  Maria H Kim; Saeed Ahmed; Mina C Hosseinipour; Thomas P Giordano; Elizabeth Y Chiao; Xiaoying Yu; Chi Nguyen; Frank Chimbwandira; Peter N Kazembe; Elaine J Abrams
Journal:  J Acquir Immune Defic Syndr       Date:  2015-04-15       Impact factor: 3.731

7.  A qualitative study of the determinants of HIV guidelines implementation in two south-eastern districts of Tanzania.

Authors:  Mary N Mwangome; Eveline Geubbels; Alison Wringe; Jim Todd; Paul Klatser; Marjolein Dieleman
Journal:  Health Policy Plan       Date:  2017-07-01       Impact factor: 3.344

8.  Identifying gaps in HIV service delivery across the diagnosis-to-treatment cascade: findings from health facility surveys in six sub-Saharan countries.

Authors:  Kathryn Church; Kazuyo Machiyama; Jim Todd; Brian Njamwea; Mary Mwangome; Vicky Hosegood; Janet Michel; Samuel Oti; Constance Nyamukapa; Amelia Crampin; Nyaguara Amek; Gertrude Nakigozi; Denna Michael; F Xavier Gómez-Olivé; Jessica Nakiyingi-Miiro; Basia Zaba; Alison Wringe
Journal:  J Int AIDS Soc       Date:  2017-01-12       Impact factor: 5.396

Review 9.  Barriers and facilitating factors to the uptake of antiretroviral drugs for prevention of mother-to-child transmission of HIV in sub-Saharan Africa: a systematic review.

Authors:  Annabelle Gourlay; Isolde Birdthistle; Gitau Mburu; Kate Iorpenda; Alison Wringe
Journal:  J Int AIDS Soc       Date:  2013-07-19       Impact factor: 5.396

10.  HIV policy and implementation: a national policy review and an implementation case study of a rural area of northern Malawi.

Authors:  Aisha N Z Dasgupta; Alison Wringe; Amelia C Crampin; Christina Chisambo; Olivier Koole; Simon Makombe; Charles Sungani; Jim Todd; Kathryn Church
Journal:  AIDS Care       Date:  2016-04-21
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  7 in total

1.  Approaches to transitioning women into and out of prevention of mother-to-child transmission of HIV services for continued ART: a systematic review.

Authors:  Tamsin K Phillips; Chloe A Teasdale; Amanda Geller; Bernadette Ng'eno; Pheposadi Mogoba; Surbhi Modi; Elaine J Abrams
Journal:  J Int AIDS Soc       Date:  2021-01       Impact factor: 5.396

2.  Uninterrupted HIV treatment for women: Policies and practices for care transitions during pregnancy and breastfeeding in Côte d'Ivoire, Lesotho and Malawi.

Authors:  Tamsin K Phillips; Halli Olsen; Chloe A Teasdale; Amanda Geller; Mamorapeli Ts'oeu; Nicole Buono; Dumbani Kayira; Bernadette Ngeno; Surbhi Modi; Elaine J Abrams
Journal:  PLoS One       Date:  2021-12-02       Impact factor: 3.240

3.  Toward elimination of mother-to-child transmission of HIV in Malawi: Findings from the Malawi Population-based HIV Impact Assessment (2015-2016).

Authors:  Evelyn Kim; Sasi Jonnalagadda; Juliana Cuervo-Rojas; Andreas Jahn; Danielle Payne; Christine West; Francis Ogollah; Alice Maida; Dumbani Kayira; Rose Nyirenda; Trudy Dobbs; Hetal Patel; Elizabeth Radin; Andrew Voetsch; Andrew Auld
Journal:  PLoS One       Date:  2022-09-01       Impact factor: 3.752

4.  Investigating the quality of HIV rapid testing practices in public antenatal health care facilities, South Africa.

Authors:  Duduzile F Nsibande; Selamawit A Woldesenbet; Adrian Puren; Peter Barron; Vincent I Maduna; Carl Lombard; Mireille Cheyip; Mary Mogashoa; Yogan Pillay; Vuyolwethu Magasana; Trisha Ramraj; Tendesayi Kufa; Gurpreet Kindra; Ameena Goga; Witness Chirinda
Journal:  PLoS One       Date:  2022-08-29       Impact factor: 3.752

5.  Investigating the implementation of differentiated HIV services and implications for pregnant and postpartum women: A mixed methods multi-country study.

Authors:  Rujeko S Chimukuche; Alison Wringe; John Songo; Farida Hassan; Lameck Luwanda; Thoko Kalua; Mosa Moshabela; Jenny Renju; Janet Seeley
Journal:  Glob Public Health       Date:  2020-07-29

6.  Influence of evolving HIV treatment guidance on CD4 counts and viral load monitoring: A mixed-methods study in three African countries.

Authors:  Jenny Renju; Brian Rice; John Songo; Farida Hassan; Rujeko Samanthia Chimukuche; Estelle McLean; Thokozani Kalua; Deborah Kajoka; Eveline Geubbels; Mosa Moshabela; Janet Seeley; Alison Wringe
Journal:  Glob Public Health       Date:  2020-08-20

7.  Implementation and experiences of integrated prevention of mother-to-child transmission services in Tanzania, Malawi and South Africa: A mixed methods study.

Authors:  Farida Hassan; Jenny Renju; John Songo; Rujeko Samanthia Chimukuche; Thokozani Kalua; Estelle McLean; Lameck Luwanda; Eveline Geubbels; Janet Seeley; Mosa Moshabela; Deborah Kajoka; Alison Wringe
Journal:  Glob Public Health       Date:  2020-10-29
  7 in total

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