Literature DB >> 3098605

Single-radial-immunodiffusion potency tests of inactivated influenza vaccines for use in man and animals.

J M Wood, J Mumford, G C Schild, R G Webster, K G Nicholson.   

Abstract

Single-radial-immunodiffusion (SRD) provides a sensitive and reproducible in vitro assay for haemagglutinin (HA) concentration in inactivated influenza vaccines. The use of SRD for human influenza vaccine standardization and application for equine and avian influenza vaccines is discussed. In clinical trials, vaccine HA concentration measured by SRD has been shown to be directly related to antibody responses and to protection against challenge. The use of SRD may considerably reduce the usage of animals for potency testing of veterinary influenza vaccines.

Entities:  

Mesh：

Substances：

Year:  1986        PMID： 3098605

Source DB:  PubMed          Journal:  Dev Biol Stand        ISSN： 0301-5149


  6 in total

1.  Virus-like particle vaccine containing hemagglutinin confers protection against 2009 H1N1 pandemic influenza.

Authors:  M Jaber Hossain; Melissa Bourgeois; Fu-Shi Quan; Aleksandr S Lipatov; Jae-Min Song; Li-Mei Chen; Richard W Compans; Ian York; Sang-Moo Kang; Ruben O Donis
Journal:  Clin Vaccine Immunol       Date:  2011-10-26

2.  Intranasal vaccination with 1918 influenza virus-like particles protects mice and ferrets from lethal 1918 and H5N1 influenza virus challenge.

Authors:  Lucy A Perrone; Attiya Ahmad; Vic Veguilla; Xiuhua Lu; Gale Smith; Jacqueline M Katz; Peter Pushko; Terrence M Tumpey
Journal:  J Virol       Date:  2009-03-25       Impact factor: 5.103

3.  Evaluation of Haemagglutinin Content by RP-HPLC to Generate Pandemic Influenza Vaccine.

Authors:  Hyunkyung Kang; Hang Sik Roh; Hyemin Song; Kwangmoon Lee; Seung-Tae Chung; Sang-Ja Ban; In Pil Mo; Beum-Soo An; Chi-Young Ahn
Journal:  Toxicol Res       Date:  2016-10-30

4.  Construction and identification of influenza plasmid pool imparting high yields to candidate vaccine viruses in Vero cell at low temperature.

Authors:  Ze Liu; Xingliang Geng; Zhaohai Cui; Weidong Li; Xia Ou; Guoyang Liao
Journal:  J Cell Mol Med       Date:  2020-09-09       Impact factor: 5.310

5.  Characterization of cross protection of Swine-Origin Influenza Virus (S-OIV) H1N1 and reassortant H5N1 influenza vaccine in BALB/c mice given a single-dose vaccination.

Authors:  Hui-Tsu Lin; Chuan-Chang Chuang; Hsieh-Ling Wu; Der-Ming Chu; Yeau-Ching Wang
Journal:  J Biomed Sci       Date:  2013-03-21       Impact factor: 8.410

6.  A novel synthetic receptor-based immunoassay for influenza vaccine quantification.

Authors:  Anwar M Hashem; Caroline Gravel; Aaron Farnsworth; Wei Zou; Michelle Lemieux; Kangwei Xu; Changgui Li; Junzhi Wang; Marie-France Goneau; Maria Merziotis; Runtao He; Michel Gilbert; Xuguang Li
Journal:  PLoS One       Date:  2013-02-12       Impact factor: 3.240
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.