Lynn G Dressler1, Gillian C Bell2, Pearl M Abernathy2, Karl Ruch3, Sheri Denslow4. 1. Mission Health Personalized Medicine & Pharmacogenomics Program; currently Independent Consultant, LGDconsulting 512, Fairview, NC 28730, USA. 2. Mission Health Personalized Medicine & Pharmacogenomics Program, Asheville, NC 28801, USA. 3. Mission Health Personalized Medicine & Pharmacogenomics Program; currently OneOME, Minneapolis, MN,55405, USA. 4. Mission Health, Mission Research Institute, Asheville, NC 28801, USA.
Abstract
Aim: Assess feasibility and perspectives of pharmacogenetic testing/PGx in rural, primary care physician (PCP) practices when PCPs are trained to interpret/apply results and testing costs are covered. Methods: Participants included PCPs who agreed to training, surveys and interviews and eligible patients who agreed to surveys and testing. 51 patients from three practices participated. Results: Prestudy, no PCP had ever ordered a PGx test. Test results demonstrated gene variations in 30% of patients, related to current medications, with PCPs reporting changes to drug management. Poststudy, test cost was still a concern, but now PCPs reported practical barriers, including the utilization of PGx results over time. PCPs and patients had favorable responses to testing. Summary: PGx testing is feasible in rural PCP practices.
Aim: Assess feasibility and perspectives of pharmacogenetic testing/PGx in rural, primary care physician (PCP) practices when PCPs are trained to interpret/apply results and testing costs are covered. Methods:Participants included PCPs who agreed to training, surveys and interviews and eligible patients who agreed to surveys and testing. 51 patients from three practices participated. Results: Prestudy, no PCP had ever ordered a PGx test. Test results demonstrated gene variations in 30% of patients, related to current medications, with PCPs reporting changes to drug management. Poststudy, test cost was still a concern, but now PCPs reported practical barriers, including the utilization of PGx results over time. PCPs and patients had favorable responses to testing. Summary: PGx testing is feasible in rural PCP practices.
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