Literature DB >> 30962328

A Novel VIM-Type Metallo-β-Lactamase Variant, VIM-60, with Increased Hydrolyzing Activity against Fourth-Generation Cephalosporins in Pseudomonas aeruginosa Clinical Isolates in Japan.

Tomomi Hishinuma1, Tatsuya Tada2, Hiroki Uchida1, Masahiro Shimojima3, Teruo Kirikae1.   

Abstract

A novel VIM-type metallo-β-lactamase variant, VIM-60, was identified in multidrug-resistant Pseudomonas aeruginosa clinical isolates in Japan. Compared with VIM-2, VIM-60 had two amino acid substitutions (Arg228Leu and His252Arg) and higher catalytic activities against fourth-generation cephalosporins. The genetic context for bla VIM-60 was intI1-bla VIM-60-aadA1-aacA31-qacEdeltaI-sulI on the chromosome.
Copyright © 2019 American Society for Microbiology.

Entities:  

Keywords:  Pseudomonas aeruginosazzm321990; fourth-generation cephalosporins; metallo-β-lactamase

Mesh：

Substances：

Year:  2019        PMID： 30962328      PMCID： PMC6535569          DOI： 10.1128/AAC.00124-19

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  14 in total

1.  Biochemical analysis of metallo-β-lactamase NDM-3 from a multidrug-resistant Escherichia coli strain isolated in Japan.

Authors:  Tatsuya Tada; Tohru Miyoshi-Akiyama; Kayo Shimada; Teruo Kirikae
Journal:  Antimicrob Agents Chemother       Date:  2014-03-31       Impact factor: 5.191

2.  Prevalence in the United States of aac(6')-Ib-cr encoding a ciprofloxacin-modifying enzyme.

Authors:  Chi Hye Park; Ari Robicsek; George A Jacoby; Daniel Sahm; David C Hooper
Journal:  Antimicrob Agents Chemother       Date:  2006-09-05       Impact factor: 5.191

Review 3.  Carbapenemases: the versatile beta-lactamases.

Authors:  Anne Marie Queenan; Karen Bush
Journal:  Clin Microbiol Rev       Date:  2007-07       Impact factor: 26.132

4.  Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase.

Authors:  Ari Robicsek; Jacob Strahilevitz; George A Jacoby; Mark Macielag; Darren Abbanat; Chi Hye Park; Karen Bush; David C Hooper
Journal:  Nat Med       Date:  2005-12-20       Impact factor: 53.440

5.  A general method for detecting and sizing large plasmids.

Authors:  B M Barton; G P Harding; A J Zuccarelli
Journal:  Anal Biochem       Date:  1995-04-10       Impact factor: 3.365

6.  Purification development and characterization of the zinc-dependent metallo-β-lactamase from Bacillus anthracis.

Authors:  Sara R Schlesinger; Sang Gon Kim; Jong-Sun Lee; Sung-Kun Kim
Journal:  Biotechnol Lett       Date:  2011-03-03       Impact factor: 2.461

7.  Quinolone resistance from a transferable plasmid.

Authors:  L Martínez-Martínez; A Pascual; G A Jacoby
Journal:  Lancet       Date:  1998-03-14       Impact factor: 79.321

8.  Fingerprint Analysis and Identification of Strains ST309 as a Potential High Risk Clone in a Pseudomonas aeruginosa Population Isolated from Children with Bacteremia in Mexico City.

Authors:  Rosario Morales-Espinosa; Gabriela Delgado; Luis F Espinosa; Dassaev Isselo; José L Méndez; Cristina Rodriguez; Guadalupe Miranda; Alejandro Cravioto
Journal:  Front Microbiol       Date:  2017-03-01       Impact factor: 5.640

9.  Exploring the Role of Residue 228 in Substrate and Inhibitor Recognition by VIM Metallo-β-lactamases.

Authors:  Maria F Mojica; S Graciela Mahler; Christopher R Bethel; Magdalena A Taracila; Magda Kosmopoulou; Krisztina M Papp-Wallace; Leticia I Llarrull; Brigid M Wilson; Steven H Marshall; Christopher J Wallace; Maria V Villegas; Michael E Harris; Alejandro J Vila; James Spencer; Robert A Bonomo
Journal:  Biochemistry       Date:  2015-05-12       Impact factor: 3.162

10.  Spread of Efflux Pump Overexpressing-Mediated Fluoroquinolone Resistance and Multidrug Resistance in Pseudomonas aeruginosa by using an Efflux Pump Inhibitor.

Authors:  Maryam Adabi; Mahshid Talebi-Taher; Leila Arbabi; Mastaneh Afshar; Sara Fathizadeh; Sara Minaeian; Niloufar Moghadam-Maragheh; Ali Majidpour
Journal:  Infect Chemother       Date:  2015-06-30
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  1 in total

1.  AcGI1, a novel genomic island carrying antibiotic resistance integron In687 in multidrug resistant Achromobacter xylosoxidans in a teaching hospital in Thailand.

Authors:  Pisut Pongchaikul; Pitak Santanirand; Svetlana Antonyuk; Craig Winstanley; Alistair C Darby
Journal:  FEMS Microbiol Lett       Date:  2020-07-01       Impact factor: 2.742
  1 in total

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