Literature DB >> 3095983

Interaction of the bacteriophage phi 29 connector protein with the viral DNA.

L Herranz, M Salas, J L Carrascosa.   

Abstract

The protein that forms the connector of phage phi 29, p10, binds to DNA. Apparently, p10 binding is not sequence specific. Nevertheless, the presence of the terminal protein (p3) covalently attached to the ends of phi 29 DNA produces a significant increase of p10 molecules bound to the DNA ends, thus suggesting a terminal protein-mediated recognition of DNA ends by the phage connector. As the p3-DNA complex is the substrate for phage phi 29 DNA packaging, these results may reflect a direct implication of the phage connector in the packaging process.

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Year:  1986        PMID： 3095983     DOI： 10.1016/0042-6822(86)90191-1

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  4 in total

1.  Role of the UL25 gene product in packaging DNA into the herpes simplex virus capsid: location of UL25 product in the capsid and demonstration that it binds DNA.

Authors:  M Ogasawara; T Suzutani; I Yoshida; M Azuma
Journal:  J Virol       Date:  2001-02       Impact factor: 5.103

2.  Alterations of the portal protein, gpB, of bacteriophage lambda suppress mutations in cosQ, the site required for termination of DNA packaging.

Authors:  Douglas J Wieczorek; Lisa Didion; Michael Feiss
Journal:  Genetics       Date:  2002-05       Impact factor: 4.562

3.  DNA conformational change induced by the bacteriophage phi 29 connector.

Authors:  J M Valpuesta; M Serrano; L E Donate; L Herranz; J L Carrascosa
Journal:  Nucleic Acids Res       Date:  1992-11-11       Impact factor: 16.971

4.  RNA-mediated specificity of DNA packaging into hybrid lambda/phi 29 proheads.

Authors:  J M Valpuesta; L E Donate; C Mier; L Herranz; J L Carrascosa
Journal:  EMBO J       Date:  1993-11       Impact factor: 11.598
  4 in total

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