Logan Vincent1, Douglas Leedy2, Sofia Carolina Masri1, Richard K Cheng3,4. 1. Division of Cardiology, Department of Medicine, University of Washington Medical Center, 1959 NE Pacific Street, Health Sciences Building, Suite No. AA-510A, Box 356422, Seattle, WA, 98195, USA. 2. Department of Internal Medicine, University of Washington Medical Center, Seattle, WA, USA. 3. Division of Cardiology, Department of Medicine, University of Washington Medical Center, 1959 NE Pacific Street, Health Sciences Building, Suite No. AA-510A, Box 356422, Seattle, WA, 98195, USA. rkcheng@uw.edu. 4. Department of Radiology, University of Washington Medical Center, Seattle, WA, USA. rkcheng@uw.edu.
Abstract
PURPOSE OF REVIEW: Cancer and cardiovascular disease are the leading causes of mortality in the USA. In this review, we highlight these shared disease pathways and provide a framework for a systems-based approach to reduce overall risk burden. RECENT FINDINGS: From traditional risk factors such as age and tobacco use to more recently recognized entities including clonal hematopoiesis, we are gaining insights into shared mechanisms. Because of these overlapping risks, providers on each level of patient care (primary care providers, cardiologists, oncologists) need to recognize and reduce these underlying risk factors. There is significant overlap in the epidemiology and risk factors for the development of cardiovascular disease and cancer, providing opportunities for joint risk factor modification.
PURPOSE OF REVIEW: Cancer and cardiovascular disease are the leading causes of mortality in the USA. In this review, we highlight these shared disease pathways and provide a framework for a systems-based approach to reduce overall risk burden. RECENT FINDINGS: From traditional risk factors such as age and tobacco use to more recently recognized entities including clonal hematopoiesis, we are gaining insights into shared mechanisms. Because of these overlapping risks, providers on each level of patient care (primary care providers, cardiologists, oncologists) need to recognize and reduce these underlying risk factors. There is significant overlap in the epidemiology and risk factors for the development of cardiovascular disease and cancer, providing opportunities for joint risk factor modification.
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