Literature DB >> 3095425

Characterization of an anti-peptide antibody that recognizes the murine analogue of the human T cell antigen receptor-T3 delta-chain.

L E Samelson, A M Weissman, F A Robey, I Berkower, R D Klausner.   

Abstract

The T cell antigen receptor consists of two disulfide-linked 40,000 to 45,000 dalton glycoproteins (alpha and beta) that contain variable and constant regions analogous to those found in immunoglobulin molecules. The antigen receptor on murine T cells is noncovalently associated with four additional nonpolymorphic structures. We describe an antibody that binds one of these molecules, a 26,000 dalton glycoprotein homologous to the human T3 delta-chain. This antibody immunoprecipitates the entire antigen receptor complex from a T cell hybridoma and from normal murine thymocytes. It represents the first reagent that can immunoprecipitate the antigen receptor complex on all murine T cells.

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Year:  1986        PMID: 3095425

Source DB:  PubMed          Journal:  J Immunol        ISSN: 0022-1767            Impact factor:   5.422


  19 in total

1.  Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor.

Authors:  L E Samelson; A F Phillips; E T Luong; R D Klausner
Journal:  Proc Natl Acad Sci U S A       Date:  1990-06       Impact factor: 11.205

2.  Subunit interactions within the T-cell antigen receptor: clues from the study of partial complexes.

Authors:  J S Bonifacino; C Chen; J Lippincott-Schwartz; J D Ashwell; R D Klausner
Journal:  Proc Natl Acad Sci U S A       Date:  1988-09       Impact factor: 11.205

3.  Identification of a monoclonal antibody specific for a murine T3 polypeptide.

Authors:  O Leo; M Foo; D H Sachs; L E Samelson; J A Bluestone
Journal:  Proc Natl Acad Sci U S A       Date:  1987-03       Impact factor: 11.205

4.  Building a multichain receptor: synthesis, degradation, and assembly of the T-cell antigen receptor.

Authors:  Y Minami; A M Weissman; L E Samelson; R D Klausner
Journal:  Proc Natl Acad Sci U S A       Date:  1987-05       Impact factor: 11.205

5.  Thy-1+ dendritic epidermal cells express T3 antigen and the T-cell receptor gamma chain.

Authors:  G Stingl; F Koning; H Yamada; W M Yokoyama; E Tschachler; J A Bluestone; G Steiner; L E Samelson; A M Lew; J E Coligan
Journal:  Proc Natl Acad Sci U S A       Date:  1987-07       Impact factor: 11.205

Review 6.  The antigen-major histocompatibility complex-T cell receptor interaction. A structural analysis.

Authors:  W V Williams; D B Weiner; S Wadsworth; M I Greene
Journal:  Immunol Res       Date:  1988       Impact factor: 2.829

7.  Subcellular localization of T-cell receptor complexes containing tyrosine-phosphorylated zeta proteins in immature CD4+CD8+ thymocytes.

Authors:  K P Kearse; D L Wiest; A Singer
Journal:  Proc Natl Acad Sci U S A       Date:  1993-03-15       Impact factor: 11.205

8.  Instability of assembled T-cell receptor complex that is associated with rapid degradation of zeta chains in immature CD4+CD8+ thymocytes.

Authors:  A Kosugi; A M Weissman; M Ogata; T Hamaoka; H Fujiwara
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-15       Impact factor: 11.205

9.  Surface expression of alternative forms of the TCR/CD3 complex.

Authors:  D J Kappes; S Tonegawa
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-01       Impact factor: 11.205

10.  Pairwise, cooperative and inhibitory interactions describe the assembly and probable structure of the T-cell antigen receptor.

Authors:  N Manolios; F Letourneur; J S Bonifacino; R D Klausner
Journal:  EMBO J       Date:  1991-07       Impact factor: 11.598

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