Chia-Jui Yen1, Ching-Hsia Hung2,3, Chung-Lan Kao4, Wei-Ming Tsai2, Shih-Hung Chan5, Hui-Ching Cheng2, Wan-Ting Jheng2, Yan-Jhen Lu2, Kun-Ling Tsai6. 1. Division of Hematology and Oncology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University , Tainan, Taiwan. 2. Department of Physical Therapy, College of Medicine, National Cheng Kung University, 701 No. 1 Ta-Hsueh Road, Tainan, Taiwan. 3. Institute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan. 4. Department of Physical Medicine and Rehabilitation, Taipei Veterans General Hospital, Taipei, Taiwan. 5. Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. 6. Department of Physical Therapy, College of Medicine, National Cheng Kung University, 701 No. 1 Ta-Hsueh Road, Tainan, Taiwan. kunlingtsai@mail.ncku.edu.tw.
Abstract
BACKGROUND: Studies have found that many chemotherapy drugs will produce multiple side effects and complications in cancer patients, especially in the case of the cardiovascular disease. This study was intended to investigate whether the exercise training intervention could improve the body composition and exercise responses of patients with head and neck (H&N) cancer who are receiving chemotherapy. METHODS: This is a randomized controlled trial. Eighty-four H&N patients were assigned to sedentary group or exercise group. The data were collected pretraining and posttraining, where the body composition, heart rate (HR), blood pressure (BP), rate-pressure product (RPP), and exercise capacity were measured. RESULTS: Our data reported that body weight and body mass index were decreased after 8 weeks of chemotherapy in the sedentary group but not in the exercise group. The decreased visceral fat and the increased skeletal muscle rate had been found in the exercise group after 8 weeks of training. In addition, in the exercise group, the HR, HR recovery, BP, BP recovery, RPP, and minutes walking distance were better than the sedentary group. Results from this study suggested exercise training significantly improved exercise responses and body composition. CONCLUSION: These findings suggested that exercise can help to promote cardiopulmonary fitness and exercise capacity for H&N cancer patients undergoing chemotherapy.
RCT Entities:
BACKGROUND: Studies have found that many chemotherapy drugs will produce multiple side effects and complications in cancer patients, especially in the case of the cardiovascular disease. This study was intended to investigate whether the exercise training intervention could improve the body composition and exercise responses of patients with head and neck (H&N) cancer who are receiving chemotherapy. METHODS: This is a randomized controlled trial. Eighty-four H&N patients were assigned to sedentary group or exercise group. The data were collected pretraining and posttraining, where the body composition, heart rate (HR), blood pressure (BP), rate-pressure product (RPP), and exercise capacity were measured. RESULTS: Our data reported that body weight and body mass index were decreased after 8 weeks of chemotherapy in the sedentary group but not in the exercise group. The decreased visceral fat and the increased skeletal muscle rate had been found in the exercise group after 8 weeks of training. In addition, in the exercise group, the HR, HR recovery, BP, BP recovery, RPP, and minutes walking distance were better than the sedentary group. Results from this study suggested exercise training significantly improved exercise responses and body composition. CONCLUSION: These findings suggested that exercise can help to promote cardiopulmonary fitness and exercise capacity for H&N cancerpatients undergoing chemotherapy.
Entities:
Keywords:
Body composition; Chemotherapy; Exercise responses; Exercise training; Head and neck cancer
Authors: Karin Gehring; Corelien Jj Kloek; Neil K Aaronson; Kasper W Janssen; Lee W Jones; Margriet M Sitskoorn; Martijn M Stuiver Journal: Clin Rehabil Date: 2017-09-08 Impact factor: 3.477
Authors: William G Albergotti; Kara S Davis; Shira Abberbock; Julie E Bauman; James Ohr; David A Clump; Dwight E Heron; Umamaheswar Duvvuri; Seungwon Kim; Jonas T Johnson; Robert L Ferris Journal: Oral Oncol Date: 2016-07-07 Impact factor: 5.337
Authors: Jonna K van Vulpen; Petra H M Peeters; Miranda J Velthuis; Elsken van der Wall; Anne M May Journal: Maturitas Date: 2015-12-28 Impact factor: 4.342
Authors: B Williams; N R Poulter; M J Brown; M Davis; G T McInnes; J F Potter; P S Sever; S McG Thom Journal: J Hum Hypertens Date: 2004-03 Impact factor: 3.012
Authors: Sara C Parke; David Michael Langelier; Jessica Tse Cheng; Cristina Kline-Quiroz; Michael Dean Stubblefield Journal: Curr Oncol Rep Date: 2022-02-19 Impact factor: 5.075
Authors: Kelcey A Bland; Sarah E Neil-Sztramko; Kendra Zadravec; Mary E Medysky; Jeffrey Kong; Kerri M Winters-Stone; Kristin L Campbell Journal: BMC Cancer Date: 2021-11-05 Impact factor: 4.430