Literature DB >> 30948887

Completion Thyroidectomy in Differentiated Thyroid Malignancy-A Prospective Analysis.

Jeyashanth Riju1, Shaji Thomas1, K R Anila2.   

Abstract

Completion thyroidectomy, being a surgically challenging procedure, choice of doing such procedure in differentiated thyroid cancer (DTC), remains unclear due to the complications involved following the procedure. So this study is intended to look into risk factors that will prompt completion thyroidectomy and surgery-related complications. A prospective analysis was done in 48 patients diagnosed with DTC during the year 2017. Completion thyroidectomy with or without neck dissection was performed as per institutional protocol. Clinico-radiological features were compared with histopathology in completion thyroidectomy specimen. The incidence of malignancy in completion thyroidectomy specimen and complications during the procedure were noted. Risk factors associated with malignancy were statistically analyzed. The incidence of malignancy in completion thyroidectomy specimen was 56.25%. Papillary carcinoma thyroid (PCT) had a statistically significant risk compared to follicular carcinoma thyroid (p = 0.042). Also, capsular invasion in primary specimen had a significant impact (p = 0.021) with odds of 7.20 times increase in incidence of malignancy and patients with age more than 55 years had a significantly increased risk of malignancy (p = 0.05). There was no statistically significant increase in complications following procedure, with respect to duration between surgeries or type of surgeries performed. Incidence of malignancy in completion thyroidectomy specimen was high. Completion thyroidectomy can be safely performed under experienced hands with an acceptable level of complications. It should be considered in places where patients are non-compliant and in those with PCT, tumor with capsular invasion and elderly patients.

Entities:  

Keywords:  Completion thyroidectomy; Differentiated thyroid cancer (DTC); Papillary carcinoma thyroid (PCT); Revision surgery; Thyroidectomy

Year:  2018        PMID: 30948887      PMCID: PMC6414589          DOI: 10.1007/s13193-018-0845-4

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  14 in total

1.  Completion thyroidectomy in differentiated thyroid cancer: When to perform?

Authors:  Abdullah Kısaoğlu; Bünyami Özoğul; Müfide Nuran Akçay; Gürkan Öztürk; Sabri Selçuk Atamanalp; Bülent Aydınlı; Salih Kara
Journal:  Ulus Cerrahi Derg       Date:  2014-03-01

2.  Papillary thyroid microcarcinoma (PTMC): prognostic factors, management and outcome in 403 patients.

Authors:  M R Pelizzo; I M Boschin; A Toniato; A Piotto; P Bernante; C Pagetta; L Rampin; D Rubello
Journal:  Eur J Surg Oncol       Date:  2006-07-26       Impact factor: 4.424

3.  Partial thyroidectomy for papillary thyroid microcarcinoma: Is completion total thyroidectomy indicated?

Authors:  C Dobrinja; M Pastoricchio; M Troian; F Da Canal; S Bernardi; B Fabris; N de Manzini
Journal:  Int J Surg       Date:  2017-05       Impact factor: 6.071

4.  Re-operative thyroid surgery: a 20-year prospective cohort study at a tertiary referral centre.

Authors:  John C Hardman; J A Smith; P Nankivell; N Sharma; J C Watkinson
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-05-11       Impact factor: 2.503

5.  Safety of completion thyroidectomy following unilateral lobectomy for well-differentiated thyroid cancer.

Authors:  Michael E Kupferman; Susan J Mandel; Liesje DiDonato; Pat Wolf; Randal S Weber
Journal:  Laryngoscope       Date:  2002-07       Impact factor: 3.325

6.  Complications of completion versus total thyroidectomy.

Authors:  Mehmet Ali Gulcelik; Bekir Kuru; Halil Dincer; Mithat Camlibel; Ulvi Murat Yuksel; Erdinc Yenidogan; Erhan Reis
Journal:  Asian Pac J Cancer Prev       Date:  2012

Review 7.  Comparison of Completion Thyroidectomy and Primary Total Surgery for Differentiated Thyroid Cancer: A Meta-Analysis.

Authors:  Yu-Jie Li; Yao-Zong Wang; Zhan-Bo Yi; Liang-Liang Chen; Xiao-Dong Zhou
Journal:  Oncol Res Treat       Date:  2015-09-27       Impact factor: 2.825

8.  Completion thyroidectomy in patients with thyroid cancer who initially underwent unilateral operation.

Authors:  Eun Sook Kim; Tae Yong Kim; Jung Min Koh; Young Il Kim; Suck Joon Hong; Won Bae Kim; Young Kee Shong
Journal:  Clin Endocrinol (Oxf)       Date:  2004-07       Impact factor: 3.478

9.  Completion thyroidectomy: predicting bilateral disease.

Authors:  Badr Ibrahim; Véronique-Isabelle Forest; Michael Hier; Alex M Mlynarek; Derin Caglar; Richard J Payne
Journal:  J Otolaryngol Head Neck Surg       Date:  2015-06-16

10.  Utility of Intraoperative Frozen Sections during Thyroid Surgery.

Authors:  Russel Kahmke; Walter T Lee; Liana Puscas; Richard L Scher; Michael J Shealy; Warner M Burch; Ramon M Esclamado
Journal:  Int J Otolaryngol       Date:  2013-01-21
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