Literature DB >> 12169901

Safety of completion thyroidectomy following unilateral lobectomy for well-differentiated thyroid cancer.

Michael E Kupferman1, Susan J Mandel, Liesje DiDonato, Pat Wolf, Randal S Weber.   

Abstract

OBJECTIVES: When a diagnosis of thyroid cancer is returned following unilateral lobectomy, removal of the contralateral lobe is frequently necessary. Morbidity for completion thyroidectomy includes a reported 2% to 5% risk of recurrent laryngeal nerve (RLN) injury and an 8% to 15% incidence of hypoparathyroidism. In this study, to determine morbidity following completion thyroidectomy, we reviewed our results of reoperative surgery among patients with thyroid cancer. STUDY
DESIGN: Retrospective chart review.
METHODS: Between 1997 and 2000, 36 consecutive patients, 32 females and 4 males, with a mean age of 43.6 years (range, 19-59 y), underwent completion thyroidectomy. Preoperative fine-needle aspiration revealed follicular derived neoplasm in 32 patients (88.9%), indeterminate in 3 patients (8.3%), and Hürthle cell neoplasm in 1 patient (2.8%). The interval between the first and second operation was a mean of 43.3 days (range, 2-103 d).
RESULTS: At the primary surgery, 29 patients (80.6%) had a follicular variant of papillary carcinoma, 6 (16.7%) had follicular carcinoma, and 1 (2.8%) had Hürthle cell carcinoma. Of these, 14 had multifocal disease. In the completion lobe, 20 patients (55.6%) had evidence of thyroid carcinoma. There was a 0% incidence of RLN injury, and the mean pre- and post-completion thyroidectomy serum calcium was 8.9 mg/dL and 8.6 mg/dL, respectively. There was one postoperative hematoma, requiring re-exploration. Five patients (13.9%) had a transient postoperative serum calcium (Ca) <8.0 mg/dL, with one being symptomatic. None required vitamin D or prolonged calcium supplementation.
CONCLUSIONS: When completion thyroidectomy is necessary for the treatment of thyroid malignancy, the procedure can be performed safely with low morbidity and is effective for diagnosing and removing occult disease in the remaining thyroid.

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Year:  2002        PMID: 12169901     DOI: 10.1097/00005537-200207000-00013

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  10 in total

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2.  Completion thyroidectomy in differentiated thyroid cancer: When to perform?

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4.  Completion Thyroidectomy in Differentiated Thyroid Malignancy-A Prospective Analysis.

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6.  Incidental parathyroidectomy during thyroid resection: incidence, risk factors, and outcome.

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7.  Utility of BRAF V600E mutation detection in cytologically indeterminate thyroid nodules.

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8.  Safety of Completion Thyroidectomy for Initially Misdiagnosed Thyroid Carcinoma.

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9.  Hürthle cell neoplasms of the thyroid: Pathologic outcomes and ultrasonographic analysis.

Authors:  Timothy J Shin; Cyrus C Rabbani; Henna D Murthy; Katie Traylor; Michael W Sim
Journal:  Laryngoscope Investig Otolaryngol       Date:  2020-10-07

10.  A favorable tumor size to define papillary thyroid microcarcinoma: an analysis of 1176 consecutive cases.

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  10 in total

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