Literature DB >> 30936951

Risk factors associated with periprosthetic joint infection after total elbow arthroplasty.

Jeremy S Somerson1, Matthew R Boylan2, Kevin T Hug3, Qais Naziri4, Carl B Paulino4, Jerry I Huang3.   

Abstract

BACKGROUND: For patients undergoing total elbow arthroplasty (TEA), the present study aimed to investigate: (i) what risk factors are associated with periprosthetic elbow infection; (ii) what is the incidence of infection after TEA; and (iii) what is the acuity with which these infections present?
METHODS: The Statewide Planning and Research Cooperative System database was used to identify all patients who underwent TEA between 2003 and 2012 in New York State. Admissions for prosthetic joint infection (PJI) were identified using ICD-9 (International Classification of Diseases, Ninth Revision, Clinical Modification) diagnosis code 996.66. Multivariate analysis was used to determine risk factors that were independently prognostic for PJI.
RESULTS: Significant risk factors for PJI included hypothyroidism [odds ratio (OR) = 2.04; p = 0.045], tobacco use disorder (OR = 3.39; p = 0.003) and rheumatoid arthritis (OR = 3.31; p < 0.001). Among the 1452 patients in the study period who underwent TEA, 3.7% (n = 54) were admitted postoperatively for PJI. There were 30 (56%) early infections, 17 (31%) delayed infections and seven (13%) late infections.
CONCLUSIONS: Pre-operative optimization of thyroid function, smoking cessation and management of rheumatoid disease may be considered in surgical candidates for TEA. The results of the present study add prognostic data to the literature that may be helpful with patient selection and risk profile analysis. LEVEL OF EVIDENCE: Level III: prognostic study.

Entities:  

Keywords:  arthroplasty; elbow; hypothyroidism; infection; rheumatoid arthritis; smoking

Year:  2017        PMID: 30936951      PMCID: PMC6434963          DOI: 10.1177/1758573217741318

Source DB:  PubMed          Journal:  Shoulder Elbow        ISSN: 1758-5732


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2.  Wound complications in thyroxine-supplemented patients following foot and ankle surgery.

Authors:  Robert Grunfeld; Allen Kunselman; Jorge Bustillo; Paul J Juliano
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4.  Outcomes of total elbow arthroplasty for rheumatoid arthritis: comparative study of three implants.

Authors:  Christopher P Little; Alastair J Graham; Georgios Karatzas; David A Woods; Andrew J Carr
Journal:  J Bone Joint Surg Am       Date:  2005-11       Impact factor: 5.284

5.  Indications and reoperation rates for total elbow arthroplasty: an analysis of trends in New York State.

Authors:  David M Gay; Stephen Lyman; Huong Do; Robert N Hotchkiss; Robert G Marx; Aaron Daluiski
Journal:  J Bone Joint Surg Am       Date:  2012-01-18       Impact factor: 5.284

6.  Characteristics and outcome of 27 elbow periprosthetic joint infections: results from a 14-year cohort study of 358 elbow prostheses.

Authors:  Y Achermann; M Vogt; C Spormann; C Kolling; C Remschmidt; J Wüst; B Simmen; A Trampuz
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7.  A multicenter, prospective, randomized, controlled trial of open reduction--internal fixation versus total elbow arthroplasty for displaced intra-articular distal humeral fractures in elderly patients.

Authors:  Michael D McKee; Christian J H Veillette; Jeremy A Hall; Emil H Schemitsch; Lisa M Wild; Robert McCormack; Bertrand Perey; Thomas Goetz; Mauri Zomar; Karyn Moon; Scott Mandel; Shirlet Petit; Pierre Guy; Irene Leung
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8.  Comparison of perioperative complications in patients with and without rheumatoid arthritis who receive total elbow replacement.

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Journal:  J Shoulder Elbow Surg       Date:  2009 Jan-Feb       Impact factor: 3.019

9.  Results after 562 total elbow replacements: a report from the Norwegian Arthroplasty Register.

Authors:  Bjørg-Tilde S Fevang; Stein A Lie; Leif I Havelin; Arne Skredderstuen; Ove Furnes
Journal:  J Shoulder Elbow Surg       Date:  2009 May-Jun       Impact factor: 3.019

10.  Preliminary evidence of immune function modulation by thyroid hormones in healthy men and women aged 55-70 years.

Authors:  Clare F Hodkinson; Ellen E A Simpson; John H Beattie; Jacqueline M O'Connor; David J Campbell; J J Strain; Julie M W Wallace
Journal:  J Endocrinol       Date:  2009-04-27       Impact factor: 4.286

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2.  Soft-tissue coverage for wound complications following total elbow arthroplasty.

Authors:  Arno A Macken; Jonathan Lans; Satoshi Miyamura; Kyle R Eberlin; Neal C Chen
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3.  A Decision Support Framework for Periprosthetic Joint Infection Treatment: A Cost-Effectiveness Analysis Using Two Modeling Approaches.

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