Literature DB >> 3093432

Semi-synthesis of A23187 (calcimycin) analogs. IV. Cation carrier properties in mitochondria of analogs with modified benzoxazole rings. Antimicrobial activity.

M Prudhomme, J Guyot, G Jeminet.   

Abstract

The transporting abilities in the mitochondrial membrane for Ca++ and Mg++ of ten semi-synthetic analogs A23187 (calcimycin) and X14885A are compared. Analogs classified as efficient divalent cation carrier retained the calcimycin antimicrobial activity against three Gram-positive strains tested.

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Year:  1986        PMID： 3093432     DOI： 10.7164/antibiotics.39.934

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  6 in total

1.  Characterization of the biosynthesis gene cluster for the pyrrole polyether antibiotic calcimycin (A23187) in Streptomyces chartreusis NRRL 3882.

Authors:  Qiulin Wu; Jingdan Liang; Shuangjun Lin; Xiufen Zhou; Linquan Bai; Zixin Deng; Zhijun Wang
Journal:  Antimicrob Agents Chemother       Date:  2010-12-20       Impact factor: 5.191

2.  Calcimycin Inhibits Cryptococcus neoformans In Vitro and In Vivo by Targeting the Prp8 Intein Splicing.

Authors:  Anil Mathew Tharappel; Zhong Li; Yan Chun Zhu; Xiangmeng Wu; Sudha Chaturvedi; Qing-Yu Zhang; Hongmin Li
Journal:  ACS Infect Dis       Date:  2022-08-10       Impact factor: 5.578

3.  2-(4-Amino-phen-yl)-1,3-benzoxazole.

Authors:  Yuan Qu; Shi-Lei Zhang; Lei Teng; Xian-You Xia; Yong Zhang
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-06-07

4.  A Novel TetR Family Transcriptional Regulator, CalR3, Negatively Controls Calcimycin Biosynthesis in Streptomyces chartreusis NRRL 3882.

Authors:  Lixia Gou; Tiesheng Han; Xiaoxia Wang; Jingxuan Ge; Wenxiu Liu; Fen Hu; Zhijun Wang
Journal:  Front Microbiol       Date:  2017-11-29       Impact factor: 5.640

5.  Crystal structure and stereochemistry study of 2-substituted benzoxazole derivatives.

Authors:  Ahmed F Mabied; Elsayed M Shalaby; Hamdia A Zayed; Esmat El-Kholy; Ibrahim S A Farag; Naima A Ahmed
Journal:  ISRN Org Chem       Date:  2014-05-13

6.  Biological activity of 3-(2-benzoxazol-5-yl)alanine derivatives.

Authors:  Katarzyna Guzow; Ewa Mulkiewicz; Michał Obuchowski; Wiesław Wiczk
Journal:  Amino Acids       Date:  2021-07-08       Impact factor: 3.520
  6 in total

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