Natalia V Oster1, Emily C Williams2, Joseph M Unger3, Polly A Newcomb4, Elizabeth N Jacobson5, M Patricia deHart6, Janet A Englund7, Annika M Hofstetter7. 1. Department of Health Services, University of Washington, 1959 NE Pacific St, Seattle, WA 98195, USA. Electronic address: nvoster@uw.edu. 2. Department of Health Services, University of Washington, 1959 NE Pacific St, Seattle, WA 98195, USA; Veterans Health Administration, VA Puget Sound, Health Services Research & Development Center of Innovation for Veteran Centered and Value-Driven Care, 1660 S. Columbian Way, Seattle, WA 98108, USA. 3. Department of Health Services, University of Washington, 1959 NE Pacific St, Seattle, WA 98195, USA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, Seattle, WA 98109, USA. 4. Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, Seattle, WA 98109, USA; Department of Epidemiology, University of Washington, 1959 NE Pacific St, Seattle, WA 98195, USA. 5. Department of Pediatrics, University of Washington, 1959 NE Pacific St, Seattle, WA 98195, USA. 6. Washington State Department of Health, 111 Israel Rd SE, Tumwater, WA 98501, USA. 7. Department of Pediatrics, University of Washington, 1959 NE Pacific St, Seattle, WA 98195, USA; Seattle Children's Research Institute, 1900 9th Ave, Seattle, WA 98101, USA.
Abstract
OBJECTIVE: Hepatitis B (HepB) vaccine is recommended at birth; however, national coverage estimates fall far below target levels. Studies describing the factors associated with infant HepB vaccination are lacking. This study aimed to identify the sociodemographic, clinical and birth hospitalization factors associated with timely receipt of the first HepB vaccine dose. STUDY DESIGN: This retrospective cohort study included Washington State infants born weighing ≥2000 g who received birth hospitalization care at an urban academic medical center between January 2008-December 2013. Multivariable logistic regression was used to estimate adjusted odds ratios (AOR) and 95% confidence intervals (CI) for associations between maternal and infant characteristics and HepB vaccine receipt during the birth hospitalization. RESULTS: Of the 9080 study infants, 75.5% received HepB vaccine during the birth hospitalization. Infants had higher odds of being vaccinated during the birth hospitalization if they were Hispanic (AOR 2.08; CI: 1.63, 2.65), non-Hispanic black (AOR 2.34; CI: 1.93, 2.84) or Asian (AOR 2.70; CI: 2.22, 3.28) compared to non-Hispanic white. Infants with a Spanish- vs. English-speaking mother (AOR 1.97; CI: 1.46, 2.68), public vs. private insurance (AOR 2.01; CI: 1.78, 2.29), and those hospitalized ≥96 h vs. 24 to <48 h (AOR 1.67; CI: 1.34, 2.09) also had higher odds of vaccination. CONCLUSIONS: Populations that are typically underserved (e.g., publicly insured, racial/ethnic minorities) had higher odds of receiving HepB vaccine during the birth hospitalization. These findings may aid in identifying high-risk infants who could benefit from targeted interventions to increase initial HepB vaccination.
OBJECTIVE:Hepatitis B (HepB) vaccine is recommended at birth; however, national coverage estimates fall far below target levels. Studies describing the factors associated with infant HepB vaccination are lacking. This study aimed to identify the sociodemographic, clinical and birth hospitalization factors associated with timely receipt of the first HepB vaccine dose. STUDY DESIGN: This retrospective cohort study included Washington State infants born weighing ≥2000 g who received birth hospitalization care at an urban academic medical center between January 2008-December 2013. Multivariable logistic regression was used to estimate adjusted odds ratios (AOR) and 95% confidence intervals (CI) for associations between maternal and infant characteristics and HepB vaccine receipt during the birth hospitalization. RESULTS: Of the 9080 study infants, 75.5% received HepB vaccine during the birth hospitalization. Infants had higher odds of being vaccinated during the birth hospitalization if they were Hispanic (AOR 2.08; CI: 1.63, 2.65), non-Hispanic black (AOR 2.34; CI: 1.93, 2.84) or Asian (AOR 2.70; CI: 2.22, 3.28) compared to non-Hispanic white. Infants with a Spanish- vs. English-speaking mother (AOR 1.97; CI: 1.46, 2.68), public vs. private insurance (AOR 2.01; CI: 1.78, 2.29), and those hospitalized ≥96 h vs. 24 to <48 h (AOR 1.67; CI: 1.34, 2.09) also had higher odds of vaccination. CONCLUSIONS: Populations that are typically underserved (e.g., publicly insured, racial/ethnic minorities) had higher odds of receiving HepB vaccine during the birth hospitalization. These findings may aid in identifying high-risk infants who could benefit from targeted interventions to increase initial HepB vaccination.
Authors: Eric E Mast; Harold S Margolis; Anthony E Fiore; Edward W Brink; Susan T Goldstein; Susan A Wang; Linda A Moyer; Beth P Bell; Miriam J Alter Journal: MMWR Recomm Rep Date: 2005-12-23
Authors: Philip J Smith; Sharon G Humiston; Edgar K Marcuse; Zhen Zhao; Christina G Dorell; Cynthia Howes; Beth Hibbs Journal: Public Health Rep Date: 2011 Jul-Aug Impact factor: 2.792
Authors: Natalia V Oster; Emily C Williams; Joseph M Unger; Polly A Newcomb; M Patricia deHart; Janet A Englund; Annika M Hofstetter Journal: J Pediatric Infect Dis Soc Date: 2021-12-31 Impact factor: 5.235
Authors: Natalia V Oster; Emily C Williams; Joseph M Unger; Polly A Newcomb; Elizabeth N Jacobson; M Patricia deHart; Janet A Englund; Annika M Hofstetter Journal: Am J Prev Med Date: 2019-10 Impact factor: 5.043