Natalia V Oster1, Emily C Williams2, Joseph M Unger3, Polly A Newcomb4, Elizabeth N Jacobson5, M Patricia deHart6, Janet A Englund5, Annika M Hofstetter5. 1. Department of Health Services, School of Public Health, University of Washington, Seattle, Washington. Electronic address: nvoster@uw.edu. 2. Department of Health Services, School of Public Health, University of Washington, Seattle, Washington; Center of Innovation for Veteran Centered and Value-Driven Care, Veterans Administration Puget Sound, Seattle, Washington. 3. Department of Health Services, School of Public Health, University of Washington, Seattle, Washington; Fred Hutchinson Cancer Research Center, Seattle, Washington. 4. Fred Hutchinson Cancer Research Center, Seattle, Washington; Department of Epidemiology, University of Washington, Seattle, Washington. 5. Department of Pediatrics, University of Washington, Seattle, Washington; Seattle Children's Research Institute, Seattle, Washington. 6. Washington State Department of Health, Olympia, Washington.
Abstract
INTRODUCTION: Current U.S. recommendations state that newborns weighing ≥2,000 grams should receive a birth dose of hepatitis B vaccine, yet approximately one quarter do not receive this first dose as scheduled. The relationship between timely receipt of the first hepatitis B vaccine and other early childhood vaccines remains unclear. METHODS: Washington State newborns (birth weight ≥2,000 grams) who received birth hospitalization care at an urban academic medical center between 2008 and 2013 were included. Multivariable logistic regression was used to assess whether hepatitis B vaccine receipt during the birth hospitalization was associated with completing the seven-vaccine series by 19 months, adjusting for select sociodemographic, clinical, and birth hospitalization characteristics. Analyses were conducted in 2017-2018. RESULTS: Of the 9,080 study participants, 75.5% received hepatitis B vaccine during the birth hospitalization, and 53.6% completed the seven-vaccine series by 19 months. Overall, 60.0% of infants vaccinated against hepatitis B during the birth hospitalization completed the seven-vaccine series by 19 months compared with 33.8% of those who were unvaccinated at discharge (p<0.001). The odds of series completion were nearly 3 times higher among infants who received versus did not receive hepatitis B vaccine during the birth hospitalization (AOR=2.92, 95% CI=2.61, 3.26). CONCLUSIONS: Infants who received hepatitis B vaccine during their birth hospitalization had higher odds of receiving all recommended vaccines by 19 months independent of other factors associated with vaccine receipt. Understanding the factors that influence this first parental vaccine decision and how hepatitis B vaccine delay or declination may affect subsequent vaccination requires further research.
INTRODUCTION: Current U.S. recommendations state that newborns weighing ≥2,000 grams should receive a birth dose of hepatitis B vaccine, yet approximately one quarter do not receive this first dose as scheduled. The relationship between timely receipt of the first hepatitis B vaccine and other early childhood vaccines remains unclear. METHODS: Washington State newborns (birth weight ≥2,000 grams) who received birth hospitalization care at an urban academic medical center between 2008 and 2013 were included. Multivariable logistic regression was used to assess whether hepatitis B vaccine receipt during the birth hospitalization was associated with completing the seven-vaccine series by 19 months, adjusting for select sociodemographic, clinical, and birth hospitalization characteristics. Analyses were conducted in 2017-2018. RESULTS: Of the 9,080 study participants, 75.5% received hepatitis B vaccine during the birth hospitalization, and 53.6% completed the seven-vaccine series by 19 months. Overall, 60.0% of infants vaccinated against hepatitis B during the birth hospitalization completed the seven-vaccine series by 19 months compared with 33.8% of those who were unvaccinated at discharge (p<0.001). The odds of series completion were nearly 3 times higher among infants who received versus did not receive hepatitis B vaccine during the birth hospitalization (AOR=2.92, 95% CI=2.61, 3.26). CONCLUSIONS:Infants who received hepatitis B vaccine during their birth hospitalization had higher odds of receiving all recommended vaccines by 19 months independent of other factors associated with vaccine receipt. Understanding the factors that influence this first parental vaccine decision and how hepatitis B vaccine delay or declination may affect subsequent vaccination requires further research.
Authors: Douglas J Opel; John Heritage; James A Taylor; Rita Mangione-Smith; Halle Showalter Salas; Victoria Devere; Chuan Zhou; Jeffrey D Robinson Journal: Pediatrics Date: 2013-11-04 Impact factor: 7.124
Authors: Sarah Schillie; Tanja Walker; Steven Veselsky; Susan Crowley; Cristina Dusek; Julie Lazaroff; Sandra A Morris; Kenneth Onye; Stephen Ko; Nancy Fenlon; Noele P Nelson; Trudy V Murphy Journal: Pediatrics Date: 2015-04-20 Impact factor: 7.124
Authors: Jason M Glanz; Nicole M Wagner; Komal J Narwaney; Courtney R Kraus; Jo Ann Shoup; Stanley Xu; Sean T O'Leary; Saad B Omer; Kathy S Gleason; Matthew F Daley Journal: Pediatrics Date: 2017-11-06 Impact factor: 7.124
Authors: Holly A Hill; Laurie D Elam-Evans; David Yankey; James A Singleton; Vance Dietz Journal: MMWR Morb Mortal Wkly Rep Date: 2016-10-07 Impact factor: 17.586
Authors: Sarah Schillie; Claudia Vellozzi; Arthur Reingold; Aaron Harris; Penina Haber; John W Ward; Noele P Nelson Journal: MMWR Recomm Rep Date: 2018-01-12
Authors: Natalia V Oster; Emily C Williams; Joseph M Unger; Polly A Newcomb; M Patricia deHart; Janet A Englund; Annika M Hofstetter Journal: J Pediatric Infect Dis Soc Date: 2021-12-31 Impact factor: 5.235