Literature DB >> 3092868

Apparent in vivo retroconversion of dietary arachidonic to linoleic acid in essential fatty acid-deficient rats.

H S Hansen, B Jensen, P von Wettstein-Knowles.   

Abstract

Essential fatty acid-deficient rats were fed ethyl [U-14C]arachidonate (308 dpm/nmol) and when a decrease in the transepidermal water loss was seen, the epidermal sphingolipids, acylglucosylceramide and acylceramide were isolated. [14C]Linoleic acid (approx. 130 dpm/nmol) was present in both lipid classes, while the substrate was only detected in the former. These results intimate that in vivo retroconversion of arachidonic to linoleic acid can be induced in the rat.

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Year:  1986        PMID： 3092868     DOI： 10.1016/0005-2760(86)90158-x

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  7 in total

1.  Which of the n-3 FA should be called essential?

Authors:  Lotte Lauritzen; Harald S Hansen
Journal:  Lipids       Date:  2003-08       Impact factor: 1.880

Review 2.  The importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrier.

Authors:  Agustí Muñoz-Garcia; Christopher P Thomas; Diane S Keeney; Yuxiang Zheng; Alan R Brash
Journal:  Biochim Biophys Acta       Date:  2013-09-07

Review 3.  Redefining essential fatty acids in the era of novel intravenous lipid emulsions.

Authors:  Lorenzo Anez-Bustillos; Duy T Dao; Gillian L Fell; Meredith A Baker; Kathleen M Gura; Bruce R Bistrian; Mark Puder
Journal:  Clin Nutr       Date:  2017-07-08       Impact factor: 7.324

Review 4.  The essentiality of arachidonic acid and docosahexaenoic acid.

Authors:  Hau D Le; Jonathan A Meisel; Vincent E de Meijer; Kathleen M Gura; Mark Puder
Journal:  Prostaglandins Leukot Essent Fatty Acids       Date:  2009-06-18       Impact factor: 4.006

5.  Essentiality of n-6 fatty acids.

Authors:  Harald S Hansen
Journal:  J Biol Chem       Date:  2019-04-26       Impact factor: 5.157

6.  The effect of varying ratios of docosahexaenoic acid and arachidonic acid in the prevention and reversal of biochemical essential fatty acid deficiency in a murine model.

Authors:  Hau D Le; Erica M Fallon; Brian T Kalish; Vincent E de Meijer; Jonathan A Meisel; Kathleen M Gura; Vania Nose; Amy H Pan; Bruce R Bistrian; Mark Puder
Journal:  Metabolism       Date:  2012-11-12       Impact factor: 8.694

7.  Lipid functions in skin: Differential effects of n-3 polyunsaturated fatty acids on cutaneous ceramides, in a human skin organ culture model.

Authors:  Alexandra C Kendall; Magdalena Kiezel-Tsugunova; Luke C Brownbridge; John L Harwood; Anna Nicolaou
Journal:  Biochim Biophys Acta Biomembr       Date:  2017-03-21       Impact factor: 3.747
  7 in total

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